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4.2.3.27: isoprene synthase

This is an abbreviated version!
For detailed information about isoprene synthase, go to the full flat file.

Word Map on EC 4.2.3.27

Reaction

dimethylallyl diphosphate
=
isoprene
+
diphosphate

Synonyms

isoprene synthase, ISPS, ispS3, PcISPS, PnISPS

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.27 isoprene synthase

Crystallization

Crystallization on EC 4.2.3.27 - isoprene synthase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
X-ray crystal structure of recombinant ISPS at 2.7 A resolution, and the structure of its complex with three Mg2+ and theunreactive substrate analogue dimethylallyl-S-thiolodiphosphate determined at 2.8 A resolution. Analysis suggests that the generation of isoprene from substrate dimethylallyl diphosphate occurs via a syn-periplanar elimination mechanism in which the diphosphate-leaving group serves as a general base