4.2.3.24: amorpha-4,11-diene synthase
This is an abbreviated version!
For detailed information about amorpha-4,11-diene synthase, go to the full flat file.
Word Map on EC 4.2.3.24
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4.2.3.24
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artemisia
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annua
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sesquiterpene
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antimalarial
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cyp71av1
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artemisinic
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terpene
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dihydroartemisinic
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trichomes
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sesquiterpenoids
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endoperoxide
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wormwood
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medicine
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artemisinin-based
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drug development
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pharmacology
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agriculture
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synthesis
- 4.2.3.24
- artemisia
- annua
-
sesquiterpene
-
antimalarial
- cyp71av1
-
artemisinic
-
terpene
-
dihydroartemisinic
- trichomes
- sesquiterpenoids
-
endoperoxide
- wormwood
- medicine
-
artemisinin-based
- drug development
- pharmacology
- agriculture
- synthesis
Reaction
Synonyms
ADS, ADS1, ADS3963, amorpha-4,11-diene synthase, amorphadiene synthase, AMS
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 4.2.3.24 - amorpha-4,11-diene synthase
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REACTION DIAGRAM
amorpha-4,11-diene + diphosphate
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(2E,6E)-farnesyl diphosphate
amorpha-4,11-diene + diphosphate
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amorpha-4,11-diene + diphosphate
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2-trans,6-trans-farnesyl diphosphate
amorpha-4,11-diene + diphosphate
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2-trans,6-trans-farnesyl diphosphate
amorpha-4,11-diene + diphosphate
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2-trans,6-trans-farnesyl diphosphate
amorpha-4,11-diene + diphosphate
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amorpha-4,11-diene is a precursor of artemisin, a three-step oxidation is necessary
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key enzyme in the biosynthetic pathway of the antimalarial drug artemisinin
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additional information
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key enzyme in the biosynthetic pathway of the antimalarial drug artemisinin
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additional information
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ADS is one of the two rate-limiting enzymes in the amorphadiene biosynthetic pathway
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