4.2.1.93: ATP-dependent NAD(P)H-hydrate dehydratase

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For detailed information about ATP-dependent NAD(P)H-hydrate dehydratase, go to the full flat file.

Word Map on EC 4.2.1.93

4.2.1.93

nadphx

epimerase

dehydrogenases

febrile

salvage

neurometabolic

epimer

neurodevelopmental

neurodegeneration

protein-truncating

reconvert

apolipoprotein

5'-phosphate

Reaction

(6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide

Synonyms

(S)-NAD(P)HX dehydratase, ADP-dependent (S)-NAD(P)H-hydrate dehydratase, ADP/ATP-dependent NAD(P)H-hydrate dehydratase, At5g19150, ATP-dependent H4NAD(P)OH dehydratase, ATP-dependent NNRD, BSU38720, Carkd, More, NAD(P)H-hydrate dehydratase, NAD(P)HX dehydratase, NAD(P)X dehydratase, NAXD, NNRD, reduced nicotinamide adenine dinucleotide hydrate dehydratase, YKL151C, YxkO

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.93 ATP-dependent NAD(P)H-hydrate dehydratase

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Results	in table
3761	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
8	Cofactor
12	Disease/ Diagnostics
1	Expression
37	General Information
4	kcat/KM [mM/s]
4	KM Value [mM]
30	Localization
6	Metals/Ions
4	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
22	Organism
2	Pathway
31	PDB ID
4	pH Optimum
1	pH Range
2	Posttranslational Modification
6	Protein Variants
4	Purification (Commentary)
2	Reaction
1	Reaction Type
16	Reference
23	Source Tissue
37	Substrates and Products (Substrate)
5	Subunits
42	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
4	Turnover Number [1/s]

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Cloned on EC 4.2.1.93 - ATP-dependent NAD(P)H-hydrate dehydratase

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gene At5g19150, sequence comparisons, functional recombinant expression of YFP-tagged enzyme in wild-type Arabidopsis thaliana leaf mesophyll via Agrobacterium tumefaciens strain C58 transformation, enzyme expression analyses, functional recombinant expression of C-terminally His6-tagged enzyme in Escherichia coli, coexpression with NNRE or PDX3

Arabidopsis thaliana

Q94AF2

748172

gene At5g19150, sequence comparisons, recombinant expression of C-terminally His6-tagged in Escherichia coli strain BL21(DE3), expression of YFP-tagged enzyme in Arabidopsis thaliana cells

Arabidopsis thaliana

Q94AF2

730041

gene Carkd, recombinant expression of Myc-His-tagged mitochondrial isozyme mCarkd, the enzyme contains a mitochondrial propeptide, in HEK-293T cells, the recombinant enzyme is not secreted (not due to dysfunction of the HEK-293T cells)

Mus musculus

Q9CZ42

747020

gene NAXD, expression analysis

Homo sapiens

Q8IW45

747751

gene YKL151C, located on chromosome 11, expression analysis

Saccharomyces cerevisiae

P36059

747751

recombinant expression as GFP-tagged enzyme in Nicotiana tabacum suspension cells, subcellular localization comprises cytosol, mitochondria, and chloroplasts

2 entries