4.2.1.93: ATP-dependent NAD(P)H-hydrate dehydratase
This is an abbreviated version!
For detailed information about ATP-dependent NAD(P)H-hydrate dehydratase, go to the full flat file.
Word Map on EC 4.2.1.93
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4.2.1.93
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nadphx
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epimerase
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dehydrogenases
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febrile
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salvage
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neurometabolic
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epimer
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neurodevelopmental
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neurodegeneration
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protein-truncating
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reconvert
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apolipoprotein
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5'-phosphate
- 4.2.1.93
-
nadphx
-
epimerase
- dehydrogenases
-
febrile
-
salvage
-
neurometabolic
-
epimer
-
neurodevelopmental
-
neurodegeneration
-
protein-truncating
-
reconvert
-
apolipoprotein
- 5'-phosphate
Reaction
Synonyms
(S)-NAD(P)HX dehydratase, ADP-dependent (S)-NAD(P)H-hydrate dehydratase, ADP/ATP-dependent NAD(P)H-hydrate dehydratase, At5g19150, ATP-dependent H4NAD(P)OH dehydratase, ATP-dependent NNRD, BSU38720, Carkd, More, NAD(P)H-hydrate dehydratase, NAD(P)HX dehydratase, NAD(P)X dehydratase, NAXD, NNRD, reduced nicotinamide adenine dinucleotide hydrate dehydratase, YKL151C, YxkO
ECTree
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Engineering
Engineering on EC 4.2.1.93 - ATP-dependent NAD(P)H-hydrate dehydratase
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additional information
the nnrd-1 mutant line GK-104E02, phenotype, overview. NNRD is dispensable for growth and development under standard conditions
additional information
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the nnrd-1 mutant line GK-104E02, phenotype, overview. NNRD is dispensable for growth and development under standard conditions
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additional information
construction of a Bacillus subtilis168 yxkO gene knockout mutant encoding a metabolite repair enzyme, transfer of the insertional mutation of the mini-Tn10 transposon to the yxkO gene from an asporogenic genetic background from a previously prepared mutant, for inactivation of the yxkO gene, an integrative vector pMUTIN4 is used. Analysis of gene yxkO knockout phenotype, overview
additional information
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construction of a Bacillus subtilis168 yxkO gene knockout mutant encoding a metabolite repair enzyme, transfer of the insertional mutation of the mini-Tn10 transposon to the yxkO gene from an asporogenic genetic background from a previously prepared mutant, for inactivation of the yxkO gene, an integrative vector pMUTIN4 is used. Analysis of gene yxkO knockout phenotype, overview
additional information
-
construction of a Bacillus subtilis168 yxkO gene knockout mutant encoding a metabolite repair enzyme, transfer of the insertional mutation of the mini-Tn10 transposon to the yxkO gene from an asporogenic genetic background from a previously prepared mutant, for inactivation of the yxkO gene, an integrative vector pMUTIN4 is used. Analysis of gene yxkO knockout phenotype, overview
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additional information
generation of an enzyme-deficient ykl151cDELTA mutant strain. In strains deleted for the YKL151C gene, concentrations of (S)-, (R)-, and cyclic NADHX are significantly increased. NAD(P)HX dehydratase deficiency leads to NAD(P)HX accumulation and NAD+ depletion in yeast, which is increased at higher gorwth temepratrure of 37°C compared to 25°C, no increase of the NADHX levels is observed in the wild-type cells at 37°C, phenotype, detailed overview. Analysis of significantly changed genes with most different expression levels between wild-type and ykl151cD strains
additional information
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generation of an enzyme-deficient ykl151cDELTA mutant strain. In strains deleted for the YKL151C gene, concentrations of (S)-, (R)-, and cyclic NADHX are significantly increased. NAD(P)HX dehydratase deficiency leads to NAD(P)HX accumulation and NAD+ depletion in yeast, which is increased at higher gorwth temepratrure of 37°C compared to 25°C, no increase of the NADHX levels is observed in the wild-type cells at 37°C, phenotype, detailed overview. Analysis of significantly changed genes with most different expression levels between wild-type and ykl151cD strains
additional information
Saccharomyces cerevisiae ATCC 204508 / S288c
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generation of an enzyme-deficient ykl151cDELTA mutant strain. In strains deleted for the YKL151C gene, concentrations of (S)-, (R)-, and cyclic NADHX are significantly increased. NAD(P)HX dehydratase deficiency leads to NAD(P)HX accumulation and NAD+ depletion in yeast, which is increased at higher gorwth temepratrure of 37°C compared to 25°C, no increase of the NADHX levels is observed in the wild-type cells at 37°C, phenotype, detailed overview. Analysis of significantly changed genes with most different expression levels between wild-type and ykl151cD strains
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