4.1.3.36: 1,4-dihydroxy-2-naphthoyl-CoA synthase

This is an abbreviated version!
For detailed information about 1,4-dihydroxy-2-naphthoyl-CoA synthase, go to the full flat file.

Word Map on EC 4.1.3.36

4.1.3.36

menaquinone

tuberculosis

crotonase

1,4-dihydroxy-2-naphthoic

hexamer

o-succinylbenzoyl-coa

o-succinylbenzoic

oxyanion

induced-fit

claisen

reorientation

tetrahedral

osb-coa

phlei

5'-triphosphate

trimer-trimer

enzyme-ligand

medicine

drug development

Reaction

Synonyms

1,4-dihydroxy-2-naphthoate synthetase, 1,4-dihydroxy-2-naphthoyl coenzyme A synthase, 1,4-dihydroxy-2-naphthoyl-CoA synthase, 1,4-dihydroxy-2-naphthoyl-coenzyme synthase, DHNA synthetase, DHNA-CoA synthase, dihydroxynaphthoate synthase, Dihydroxynaphthoic acid synthetase, MenB, naphthoate synthase, naphthoate synthase (MenB), Rv0548c, synthase, 1,4-dihydroxy-2-naphthoate

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.3 Oxo-acid-lyases

4.1.3.36 1,4-dihydroxy-2-naphthoyl-CoA synthase

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Results	in table
14675	AA Sequence
3	Application
1	CAS Registry Number
13	Cloned(Commentary)
3	Cofactor
10	Crystallization (Commentary)
9	General Information
2	General Stability
29	IC50 Value
57	Inhibitors
10	kcat/KM [mM/s]
10	Ki Value [mM]
10	KM Value [mM]
1	Localization
4	Metals/Ions
3	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
28	Organism
6	Pathway
142	PDB ID
5	pH Optimum
20	Protein Variants
18	Purification (Commentary)
5	Reaction
6	Reaction Type
26	Reference
3	Source Tissue
1	Specific Activity [micromol/min/mg]
2	Storage Stability
33	Substrates and Products (Substrate)
7	Subunits
42	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
10	Turnover Number [1/s]

KM Value

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KM Value on EC 4.1.3.36 - 1,4-dihydroxy-2-naphthoyl-CoA synthase

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0.106

2-(3-carboxypropyl)-benzoyl-CoA

Mycobacterium tuberculosis

P9WNP5

wild type protein protein, pH 7.0, 25°C

714273

0.0031 - 0.0402

2-succinylbenzoyl-CoA

4 entries

0.0028 - 0.0433

o-succinylbenzoate

4 entries

0.0259

o-succinylbenzoyl-CoA

Escherichia coli

pH 7.0, 25°C

714273