Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.1.3.36: 1,4-dihydroxy-2-naphthoyl-CoA synthase

This is an abbreviated version!
For detailed information about 1,4-dihydroxy-2-naphthoyl-CoA synthase, go to the full flat file.

Word Map on EC 4.1.3.36

Reaction

4-(2-carboxyphenyl)-4-oxobutanoyl-CoA
=
1,4-dihydroxy-2-naphthoyl-CoA
 +
H2O

Synonyms

1,4-dihydroxy-2-naphthoate synthetase, 1,4-dihydroxy-2-naphthoyl coenzyme A synthase, 1,4-dihydroxy-2-naphthoyl-CoA synthase, 1,4-dihydroxy-2-naphthoyl-coenzyme synthase, DHNA synthetase, DHNA-CoA synthase, dihydroxynaphthoate synthase, Dihydroxynaphthoic acid synthetase, MenB, naphthoate synthase, naphthoate synthase (MenB), Rv0548c, synthase, 1,4-dihydroxy-2-naphthoate

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.36 1,4-dihydroxy-2-naphthoyl-CoA synthase

KI Value

KI Value on EC 4.1.3.36 - 1,4-dihydroxy-2-naphthoyl-CoA synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0013
1-hydroxy-2-naphthoyl-CoA
-
pH 7,0, 23°C
0.0031
2,3-dihydroxybenzoyl-CoA
-
pH 7,0, 23°C
0.0022
2,4-dihydroxybenzoyl-CoA
-
pH 7,0, 23°C
0.000049
2-CoA-4-(2,4-dichlorophenyl)-4-oxobutanoic acid
pH 7.4, 25°C
0.000097
2-CoA-4-(2-chlorophenyl)-4-oxobutanoic acid
pH 7.4, 25°C
0.00035
2-CoA-4-(4-dichlorophenyl)-4-oxobutanoic acid
pH 7.4, 25°C
0.0091
methyl (2Z)-(2-oxo-2H-1,4-benzoxazin-3(4H)-ylidene)ethanoate
-
non-competitive inhibitor, pH not specified in the publication, temperature not specified in the publication
0.0225
methyl (2Z)-(6-chloro-2-oxo-2H-1,4-benzoxazin-3(4H)-ylidene)ethanoate
-
non-competitive inhibitor, pH not specified in the publication, temperature not specified in the publication
0.0115
methyl (2Z)-(6-fluoro-2-oxo-2H-1,4-benzoxazin-3(4H)-ylidene)ethanoate
-
non-competitive inhibitor , pH not specified in the publication, temperature not specified in the publication
0.006
salicylyl-CoA
-
pH 7,0, 23°C