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3.8.1.10: 2-haloacid dehalogenase (configuration-inverting)

This is an abbreviated version!
For detailed information about 2-haloacid dehalogenase (configuration-inverting), go to the full flat file.

Word Map on EC 3.8.1.10

Reaction

(R)-2-haloacid
+
H2O
=
(S)-2-hydroxyacid
+
halide

Synonyms

2-HAD, 2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, DL DEX 113, DL-2-haloacid dehalogenase, DL-2-haloacid dehalogenase (inversion of configuration), DL-2-haloacid halidohydrolase (inversion of configuration), DL-DEX, DL-DEX 113, DL-DEX Mb, DL-DEXi, L-2-haloacid dehalogenase, L-DEX, L-DEX YL, ps-2-HAD

ECTree

     3 Hydrolases
         3.8 Acting on halide bonds
             3.8.1 In carbon-halide compounds
                3.8.1.10 2-haloacid dehalogenase (configuration-inverting)

Expression

Expression on EC 3.8.1.10 - 2-haloacid dehalogenase (configuration-inverting)

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
dehalogenase activity of the cell-free extracts obtained from AW-1T cells grown in the presence of chlorate is up to 3.5fold higher than the cell-free extracts obtained from AW-1T cells grown in the presence of oxygen
high constitutive expression of the L-DEX gene. The expression of the L-DEX gene is relatively stable, and the highest upregulation (about 22fold) is observed in the cultures amended with L-2-chloropropionate after 18 h, which then decreases