3.8.1.10: 2-haloacid dehalogenase (configuration-inverting)

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For detailed information about 2-haloacid dehalogenase (configuration-inverting), go to the full flat file.

Word Map on EC 3.8.1.10

3.8.1.10

lymphedema

bioimpedance

cancer-related

dehalogenation

l-2-haloalkanoic

2-haloacids

l-2-chloropropionate

alpha-carbon

monochloroacetate

decongestive

autotrophicus

xanthobacter

synthesis

Reaction

Synonyms

2-HAD, 2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, DL DEX 113, DL-2-haloacid dehalogenase, DL-2-haloacid dehalogenase (inversion of configuration), DL-2-haloacid halidohydrolase (inversion of configuration), DL-DEX, DL-DEX 113, DL-DEX Mb, DL-DEXi, L-2-haloacid dehalogenase, L-DEX, L-DEX YL, ps-2-HAD

ECTree

3 Hydrolases

3.8 Acting on halide bonds

3.8.1 In carbon-halide compounds

3.8.1.10 2-haloacid dehalogenase (configuration-inverting)

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Results	in table
12	AA Sequence
1	Application
1	CAS Registry Number
6	Cloned(Commentary)
2	Crystallization (Commentary)
4	Expression
4	General Information
25	Inhibitors
4	Ki Value [mM]
16	KM Value [mM]
7	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
122	Organism
12	PDB ID
7	pH Optimum
1	pH Range
1	pH Stability
1	pI Value
21	Protein Variants
6	Purification (Commentary)
4	Reaction
1	Reaction Type
45	Reference
1	Source Tissue
4	Specific Activity [micromol/min/mg]
1	Storage Stability
147	Substrates and Products (Substrate)
12	Subunits
27	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]

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Cloned on EC 3.8.1.10 - 2-haloacid dehalogenase (configuration-inverting)

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expression in Escherichia coli

2 entries

expression in Escherichia coli, no significant sequence similarity between enzyme and L-2-haloacid dehalogenase is found, however, enzyme has significant sequence similarity with D-2-haloacid dehalogenase fom Pseudomonas putide AJ1

Pseudomonas sp.

O06652

648283

gene located on pFL40

Achromobacter xylosoxidans

648285

recombinant expression of wild-type and mutant enzymes

Pseudomonas syringae

Q88B12

732999

recombinant expresssion of enzyme DL-DEX Mb in Escherichia coli

Methylobacterium sp.

A6BM74

733212