3.6.1.23: dUTP diphosphatase

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For detailed information about dUTP diphosphatase, go to the full flat file.

Reaction

Synonyms

DCD-DUT, dCTP deaminase-dUTPase, dCTP deaminase:dUTPase, deoxyuridine 5'-triphosphate, deoxyuridine 5'-triphosphate nucleotide hydrolase, deoxyuridine 5'-triphosphate nucleotidohydrolase, deoxyuridine 5'-triphosphate pyrophosphatase, deoxyuridine 50-triphosphate nucleotidohydrolase, deoxyuridine 5�-triphosphate nucleotidohydrolase, deoxyuridine nucleotidohydrolase, deoxyuridine triphosphatase, deoxyuridine triphosphate nucleotidohydrolase, deoxyuridine triphosphate pyrophosphatase, deoxyuridine-5'-triphosphate nucleotidohydrolase, deoxyuridine-triphosphate pyrophosphatase, desoxyuridine 5'-triphosphatase, desoxyuridine 5'-triphosphate nucleotidohydrolase, desoxyuridine-triphosphatase, DURP, DUT, DUT-N, DUT1, dUTP nucleotidohydrolase, dUTP pyrophosphatase, dUTPae, dUTPase, dUTPase-dUDPase, dUTPase-related protein, E165R, More, ORF 54, ORF8, P18, PIP4, Pr95, STSV2_30, Tb927.7.5160, U45, YncF, YosS

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.23 dUTP diphosphatase

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Results	in table
2	Activating Compound
33833	AA Sequence
32	Application
1	CAS Registry Number
73	Cloned(Commentary)
44	Crystallization (Commentary)
670	Disease/ Diagnostics
2	Expression
22	General Information
2	General Stability
88	IC50 Value
352	Inhibitors
62	kcat/KM [mM/s]
173	Ki Value [mM]
139	KM Value [mM]
26	Localization
89	Metals/Ions
65	Molecular Weight [Da]
135	Natural Substrates/ Products (Substrates)
487	Organism
10	Pathway
409	PDB ID
23	pH Optimum
12	pH Range
1	pH Stability
5	pI Value
1	Posttranslational Modification
99	Protein Variants
71	Purification (Commentary)
19	Reaction
1	Reaction Type
210	Reference
50	Source Tissue
20	Specific Activity [micromol/min/mg]
8	Storage Stability
329	Substrates and Products (Substrate)
92	Subunits
261	Synonyms
1	Systematic Name
22	Temperature Optimum [°C]
5	Temperature Range [°C]
19	Temperature Stability [°C]
95	Turnover Number [1/s]

General Stability

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General Stability on EC 3.6.1.23 - dUTP diphosphatase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

dUMP protects against tryptic digestion, slight fragmentation caused by frequent freezing and thawing that does not affect the activity

Drosophila melanogaster

-

656212

stable to freezing and thawing

Escherichia coli

-

209964