3.6.1.23: dUTP diphosphatase

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For detailed information about dUTP diphosphatase, go to the full flat file.

Reaction

Synonyms

DCD-DUT, dCTP deaminase-dUTPase, dCTP deaminase:dUTPase, deoxyuridine 5'-triphosphate, deoxyuridine 5'-triphosphate nucleotide hydrolase, deoxyuridine 5'-triphosphate nucleotidohydrolase, deoxyuridine 5'-triphosphate pyrophosphatase, deoxyuridine 50-triphosphate nucleotidohydrolase, deoxyuridine 5�-triphosphate nucleotidohydrolase, deoxyuridine nucleotidohydrolase, deoxyuridine triphosphatase, deoxyuridine triphosphate nucleotidohydrolase, deoxyuridine triphosphate pyrophosphatase, deoxyuridine-5'-triphosphate nucleotidohydrolase, deoxyuridine-triphosphate pyrophosphatase, desoxyuridine 5'-triphosphatase, desoxyuridine 5'-triphosphate nucleotidohydrolase, desoxyuridine-triphosphatase, DURP, DUT, DUT-N, DUT1, dUTP nucleotidohydrolase, dUTP pyrophosphatase, dUTPae, dUTPase, dUTPase-dUDPase, dUTPase-related protein, E165R, More, ORF 54, ORF8, P18, PIP4, Pr95, STSV2_30, Tb927.7.5160, U45, YncF, YosS

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.23 dUTP diphosphatase

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Results	in table
2	Activating Compound
33833	AA Sequence
32	Application
1	CAS Registry Number
73	Cloned(Commentary)
44	Crystallization (Commentary)
670	Disease/ Diagnostics
2	Expression
22	General Information
2	General Stability
88	IC50 Value
352	Inhibitors
62	kcat/KM [mM/s]
173	Ki Value [mM]
139	KM Value [mM]
26	Localization
89	Metals/Ions
65	Molecular Weight [Da]
135	Natural Substrates/ Products (Substrates)
487	Organism
10	Pathway
409	PDB ID
23	pH Optimum
12	pH Range
1	pH Stability
5	pI Value
1	Posttranslational Modification
99	Protein Variants
71	Purification (Commentary)
19	Reaction
1	Reaction Type
210	Reference
50	Source Tissue
20	Specific Activity [micromol/min/mg]
8	Storage Stability
329	Substrates and Products (Substrate)
92	Subunits
261	Synonyms
1	Systematic Name
22	Temperature Optimum [°C]
5	Temperature Range [°C]
19	Temperature Stability [°C]
95	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 3.6.1.23 - dUTP diphosphatase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, 7 days, 2% loss of activity of HSV-1 induced dUTPase

Human alphaherpesvirus 1

-

209974

-20°C, 7 days, 70% loss of activity of uninduced dUTPase

Homo sapiens

-

209974

-20°C, stable for several months

Rattus norvegicus

-

209980

-70°C, 50 mM HEPES, pH 7.2, 150 mM NaCl, 2 mM dithiothreitol

Methanocaldococcus jannaschii

Q57872

648212

-70°C, stable for at least 3 months

Drosophila melanogaster

-

656212

-70°C, stable for at least 5 months

Escherichia coli

-

209964

-80°C, stable for 1 year

Vaccinia virus

-

209987

0°C, stable for at least 3 months

Escherichia coli

-

209964