3.5.1.99: fatty acid amide hydrolase

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For detailed information about fatty acid amide hydrolase, go to the full flat file.

Word Map on EC 3.5.1.99

3.5.1.99

endocannabinoids

cannabinoids

pain

lipase

agonist

monoacylglycerol

2-arachidonoylglycerol

anxiety

analgesic

cannabis

n-acylethanolamines

vanilloid

2-arachidonoyl

ethanolamide

palmitoylethanolamide

carbamate

rimonabant

hyperalgesia

reward

tone

nociceptive

cannabimimetic

n-arachidonoylethanolamine

marijuana

anxiolytic

nape-pld

antinociceptive

oleoylethanolamide

emotional

neuropathic

delta9-tetrahydrocannabinol

amidase

amygdalar

medicine

catalepsy

pharmacology

anti-allodynic

anxiolytic-like

monoglyceride

cannabidiol

psychoactive

sleep-inducing

phytocannabinoids

anxiety-like

arachidonyl

monoacyl

capsazepine

aversive

tetrahydrocannabinol

drug development

anti-hyperalgesic

neuromodulatory

fluorophosphonate

Reaction

Synonyms

AAH, anandamide amidohydrolase, AtFAAH, endocannabinoid-degrading enzyme, FA amide hydrolase, FAAH, FAAH-1, FAAH-2, fatty acid amide hydrolase, fatty-acid amide hydrolase, hFAAH, oleamide hydrolase

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.99 fatty acid amide hydrolase

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Results	in table
418	AA Sequence
9	Application
1	CAS Registry Number
24	Cloned(Commentary)
4	Crystallization (Commentary)
581	Disease/ Diagnostics
1	Expression
48	General Information
1	General Stability
580	IC50 Value
893	Inhibitors
146	Ki Value [mM]
52	KM Value [mM]
42	Localization
4	Molecular Weight [Da]
61	Natural Substrates/ Products (Substrates)
472	Organism
1	Pathway
36	PDB ID
19	pH Optimum
1	pH Range
1	pH Stability
3	Posttranslational Modification
36	Protein Variants
6	Purification (Commentary)
4	Reaction
87	Reference
89	Source Tissue
2	Specific Activity [micromol/min/mg]
200	Substrates and Products (Substrate)
8	Subunits
94	Synonyms
1	Systematic Name
17	Temperature Optimum [°C]
41	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.5.1.99 - fatty acid amide hydrolase

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0.00908

Homo sapiens

Vmax, substrate: N-(6-methoxypyridin-3-yl)decanamide, pH 8.0, 30°C

752472

0.0213

Homo sapiens

Vmax, substrate: N-(6-methoxypyridin-3-yl)octanamide, pH 8.0, 30°C

752472