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3.5.1.99: fatty acid amide hydrolase

This is an abbreviated version!
For detailed information about fatty acid amide hydrolase, go to the full flat file.

Word Map on EC 3.5.1.99

Reaction

anandamide
+
H2O
=
arachidonic acid
+
ethanolamine

Synonyms

AAH, anandamide amidohydrolase, AtFAAH, endocannabinoid-degrading enzyme, FA amide hydrolase, FAAH, FAAH-1, FAAH-2, fatty acid amide hydrolase, fatty-acid amide hydrolase, hFAAH, oleamide hydrolase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.99 fatty acid amide hydrolase

Source Tissue

Source Tissue on EC 3.5.1.99 - fatty acid amide hydrolase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
primary
Manually annotated by BRENDA team
-
role of FAAH in epithelial cells of the choroid plexus may be to control the concentration of oleamide in the cerebrospinal fluid. FAAH may exert an important regulatory role in shaping the duration and magnitude of the sleep-inducing effect of endogenously or exogenously derived oleamide
Manually annotated by BRENDA team
highly expressed
Manually annotated by BRENDA team
-
peripheral
Manually annotated by BRENDA team
additional information