3.5.1.48: acetylspermidine deacetylase

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For detailed information about acetylspermidine deacetylase, go to the full flat file.

Word Map on EC 3.5.1.48

3.5.1.48

deacetylases

deacetylation

hdac11

mycoplana

ramosa

pharmacology

drug development

Reaction

Synonyms

acetylpolyamine amidohydrolase, APAH, HDAC10, histone deacetylase 10, N1-acetylspermidine amidohydrolase, N1-acetylspermidine deacetylase, N8-acetyl-monoacetylspermidine deacetylase, N8-acetylspermidine deacetylase, polyamine deacetylase, zHDAC10

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.48 acetylspermidine deacetylase

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Results	in table
2	Activating Compound
102	AA Sequence
2	Application
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
220	Disease/ Diagnostics
8	General Information
86	Inhibitors
35	kcat/KM [mM/s]
23	Ki Value [mM]
44	KM Value [mM]
8	Localization
5	Metals/Ions
6	Natural Substrates/ Products (Substrates)
15	Organism
26	PDB ID
6	pH Optimum
1	pH Stability
6	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
15	Reference
24	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
54	Substrates and Products (Substrate)
1	Subunits
21	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Stability [°C]
37	Turnover Number [1/s]

Purification

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Purification on EC 3.5.1.48 - acetylspermidine deacetylase

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29fold, chromatography techniques

partial

recombinant TEV-cleavable N-terminal His-MBP-tagged enzyme from Escherichia coli strain BL21(DE3) by amylose affinity chromatography and anion exchange chromatography, the MBP-tag is not cleaved off

Homo sapiens

Q969S8

754843

recombinant TEV-cleavable N-terminal His-MBP-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by amylose affinity chromatography, TEV protease is used to remove the His-MBP-tag, followed by anion exchange chromatography and gel filtration

Danio rerio

F1QCV2

754843