3.4.24.19: procollagen C-endopeptidase

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For detailed information about procollagen C-endopeptidase, go to the full flat file.

Word Map on EC 3.4.24.19

3.4.24.19

procollagens

metalloproteinases

proteinases

chordin

fibril

gastrulation

c-propeptide

astacins

metalloprotease

fibrillar

pcpe-1

decapentaplegic

desulfitobacterium

pentachlorophenol

urchin

sialoprotein

hafniense

meprin

gastrula

astacin-like

n-proteinase

pcolce

imperfecta

dorsoventral

bmp4

sialophosphoprotein

dechlorination

prodomains

noggin

metzincins

osteoinductive

medicine

Reaction

cleavage of the C-terminal propeptide at Ala-/-Asp in type I and II procollagens and at Arg-/-Asp in type III =

Synonyms

BMP-1, BMP1, bone morphogenetic protein 1, bone morphogenetic protein 1/tolloid, bone morphogenetic protein-1, bone morphogenic protein 1, Carboxy-terminal endopeptidase, carboxy-terminal procollagen peptidase, Carboxyl procollagen peptidase, carboxyl-procollagen peptidase, Carboxyprocollagen peptidase, dorsal-ventral patterning protein tolloid, mammalian tolloid, Mammalian tolloid protein, More, mTId, MtlD, PCP, PCP-1, PCP-2, Peptidase, procollagen C-terminal, procollagen C-peptidase, Procollagen C-proteinase, Procollagen C-terminal proteinase, Procollagen carboxy-terminal proteinase, Procollagen carboxypeptidase, Procollagen peptidase, Proteinase, procollagen C-terminal, suBMP-1, TId, Tld, tolloid, Type I procollagen C-proteinase, XBMP1-A, XBMP1-B

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.19 procollagen C-endopeptidase

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Results	in table
22	Activating Compound
16	AA Sequence
4	Application
1	CAS Registry Number
12	Cloned(Commentary)
175	Disease/ Diagnostics
17	General Information
2	General Stability
133	IC50 Value
236	Inhibitors
4	kcat/KM [mM/s]
6	KM Value [mM]
9	Localization
7	Metals/Ions
16	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
45	Organism
13	PDB ID
4	pH Optimum
1	pH Range
3	pH Stability
11	Protein Variants
10	Purification (Commentary)
1	Reaction
1	Reaction Type
45	Reference
56	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
81	Substrates and Products (Substrate)
3	Subunits
117	Synonyms
1	Temperature Optimum [°C]
5	Turnover Number [1/s]

Source Tissue

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Source Tissue on EC 3.4.24.19 - procollagen C-endopeptidase

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adenocarcinoma cell

Homo sapiens

gastric epithelial adenocarcinoma stimulated with Helicobacter pylori

tumor endothelial cells of malignant colorectal tissues

mTld

aortic root

egg

mTld and BMP-1

mTld and BMP-1

mTld and BMP-1

BMP1 is expressed in the ovary throughout early fetal stages to adulthood. Within ovine ovaries, immunohistochemical localization shows that BMP1 is present in granulosa cells at all stages of follicular development, from primordial to large antral follicles, and that the levels of BMP1 are not affected by the final follicle selection mechanism

mTld and BMP-1

additional information

3 entries