3.4.24.19: procollagen C-endopeptidase

This is an abbreviated version!
For detailed information about procollagen C-endopeptidase, go to the full flat file.

Word Map on EC 3.4.24.19

3.4.24.19

procollagens

metalloproteinases

proteinases

chordin

fibril

gastrulation

c-propeptide

astacins

metalloprotease

fibrillar

pcpe-1

decapentaplegic

desulfitobacterium

pentachlorophenol

urchin

sialoprotein

hafniense

meprin

gastrula

astacin-like

n-proteinase

pcolce

imperfecta

dorsoventral

bmp4

sialophosphoprotein

dechlorination

prodomains

noggin

metzincins

osteoinductive

medicine

Reaction

cleavage of the C-terminal propeptide at Ala-/-Asp in type I and II procollagens and at Arg-/-Asp in type III =

Synonyms

BMP-1, BMP1, bone morphogenetic protein 1, bone morphogenetic protein 1/tolloid, bone morphogenetic protein-1, bone morphogenic protein 1, Carboxy-terminal endopeptidase, carboxy-terminal procollagen peptidase, Carboxyl procollagen peptidase, carboxyl-procollagen peptidase, Carboxyprocollagen peptidase, dorsal-ventral patterning protein tolloid, mammalian tolloid, Mammalian tolloid protein, More, mTId, MtlD, PCP, PCP-1, PCP-2, Peptidase, procollagen C-terminal, procollagen C-peptidase, Procollagen C-proteinase, Procollagen C-terminal proteinase, Procollagen carboxy-terminal proteinase, Procollagen carboxypeptidase, Procollagen peptidase, Proteinase, procollagen C-terminal, suBMP-1, TId, Tld, tolloid, Type I procollagen C-proteinase, XBMP1-A, XBMP1-B

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.19 procollagen C-endopeptidase

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Results	in table
22	Activating Compound
16	AA Sequence
4	Application
1	CAS Registry Number
12	Cloned(Commentary)
175	Disease/ Diagnostics
17	General Information
2	General Stability
133	IC50 Value
236	Inhibitors
4	kcat/KM [mM/s]
6	KM Value [mM]
9	Localization
7	Metals/Ions
16	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
45	Organism
13	PDB ID
4	pH Optimum
1	pH Range
3	pH Stability
11	Protein Variants
10	Purification (Commentary)
1	Reaction
1	Reaction Type
45	Reference
56	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
81	Substrates and Products (Substrate)
3	Subunits
117	Synonyms
1	Temperature Optimum [°C]
5	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 3.4.24.19 - procollagen C-endopeptidase

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100000

Gallus gallus

SDS-PAGE, mature N-gycosylated enzyme

668838

102000

Gallus gallus

1 * 102000, chicken, SDS-PAGE

31033

10700

Xenopus laevis

immunoblotting, XBMP1-B in adults

110200

XBMP1-A

111600

mTld

125000

mouse, gel filtration

31042

20800

Homo sapiens

SDS-PAGE, purified CUB3-EGF2 PCP construct

43000

gel filtration

63000

XBMP1-A in unfertilized eggs

668838

71890

Strongylocentrotus purpuratus

calculated

80000

80670

XBMP1-B

82900

prepro-BMP1

97000 - 110000

gel filtration, PAGE