3.4.22.B79: nsP2 protease
This is an abbreviated version!
For detailed information about nsP2 protease, go to the full flat file.
Word Map on EC 3.4.22.B79
-
3.4.22.B79
-
polyproteins
-
viruses
-
alphavirus
-
chikungunya
-
replicase
-
sindbis
-
chikv
-
nsp1
-
semliki
-
subgenomic
-
positive-stranded
-
venezuelan
-
hp-prrsv
-
papain-like
-
noncytopathic
-
plus-stranded
-
positive-sense
-
minus-strand
-
analysis
-
3c-like
-
drug development
-
autoprotease
-
medicine
- 3.4.22.B79
- polyproteins
- viruses
- alphavirus
-
chikungunya
-
replicase
-
sindbis
-
chikv
- nsp1
-
semliki
-
subgenomic
-
positive-stranded
-
venezuelan
-
hp-prrsv
-
papain-like
-
noncytopathic
-
plus-stranded
-
positive-sense
-
minus-strand
- analysis
-
3c-like
- drug development
-
autoprotease
- medicine
Reaction
the enzymes processes the alphavirus nonstructural polyprotein (nsP1234). The enzyme from Venezuelan equine encephalitis virus shwos a preferens for Gly or Als in position P1', Ala or Cys in P1, and Gly in P2 =
Synonyms
non-structural polyprotein 2, nonstructural polyprotein, nonstructural protein, nonstructural protein 2, ns polyprotein, nsP2, nsP2 protease, nsp2 protein, nsp2pro, p39 nsp2 protease
ECTree
3.4.22.B79 nsP2 proteaseAdvanced search results
results (
results (Turnover Number
Turnover Number on EC 3.4.22.B79 - nsP2 protease
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.00052
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
mutant C478A, pH 7.5, 37°C
0.00076
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
mutant W549F, pH 7.5, 37°C
0.00084
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
presence of glutathione disulfide, pH 7.5, 37°C
0.00164
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
mutant S482A, pH 7.5, 37°C
0.0027
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
full-length enzyme, pH 7.5, 37°C
0.0032
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
mutant W549A, pH 7.5, 37°C
0.0033
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
truncated enzyme, pH 7.5, 37°C
0.0046
2-(N-methylamino)benzoyl-AGAGIIETk(Dnp)
-
wild-type enzyme, pH 7.5, 37°C
0.0013
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
mutant W549F, pH 7.5, 37°C
0.00142
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
presence of glutathione disulfide, pH 7.5, 37°C
0.0021
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
mutant S482A, pH 7.5, 37°C
0.0024
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
wild-type enzyme, pH 7.5, 37°C
0.0029
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
truncated enzyme, pH 7.5, 37°C
0.0031
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
mutant C478A, pH 7.5, 37°C
0.0034
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
full-length enzyme, pH 7.5, 37°C
0.0075
2-(N-methylamino)benzoyl-AGCGIIETk(Dnp)
-
mutant W549A, pH 7.5, 37°C
0.00068
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
presence of glutathione disulfide, pH 7.5, 37°C
0.0011
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
truncated enzyme, pH 7.5, 37°C
0.0013
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
mutant W549F, pH 7.5, 37°C
0.0014
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
mutant S482A, pH 7.5, 37°C
0.0015
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
mutant C478A, pH 7.5, 37°C
0.0016
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
wild-type enzyme, pH 7.5, 37°C
0.0017
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
mutant W549A, pH 7.5, 37°C
0.0019
2-(N-methylamino)benzoyl-AGGGIIETk(Dnp)
-
full-length enzyme, pH 7.5, 37°C
