3.4.22.62: caspase-9
This is an abbreviated version!
For detailed information about caspase-9, go to the full flat file.
Word Map on EC 3.4.22.62
-
3.4.22.62
-
caspase-3
-
bcl-2
-
parp
-
anti-apoptotic
-
pro-apoptotic
-
tunel
-
necrosis
-
apoptosis-related
-
caspase-dependent
-
apoptosis-inducing
-
jnk
-
apaf-1
-
annexin
-
extrinsic
-
cyclin
-
leukemia
-
bid
-
neuroprotective
-
depolarization
-
polyadp-ribose
-
survivin
-
hoechst
-
z-vad-fmk
-
antiproliferative
-
adp-ribose
-
xiap
-
iodide
-
deoxynucleotidyl
-
mitochondria-dependent
-
mitochondria-mediated
-
cisplatin
-
dutp
-
fadd
-
procaspase-3
-
caspase-mediated
-
pan-caspase
-
fas-mediated
-
trail
-
fas-associated
-
trail-induced
-
bcl-2-associated
-
apoptogenic
-
pharmacology
-
cdc25c
-
puma
-
transferase-mediated
-
executioner
-
factor-related
-
deltapsim
-
medicine
-
tunel-positive
-
sub-g1
- 3.4.22.62
- caspase-3
- bcl-2
- parp
-
anti-apoptotic
-
pro-apoptotic
-
tunel
- necrosis
-
apoptosis-related
-
caspase-dependent
-
apoptosis-inducing
- jnk
- apaf-1
-
annexin
-
extrinsic
- cyclin
- leukemia
- bid
-
neuroprotective
-
depolarization
-
polyadp-ribose
- survivin
-
hoechst
- z-vad-fmk
-
antiproliferative
- adp-ribose
- xiap
- iodide
-
deoxynucleotidyl
-
mitochondria-dependent
-
mitochondria-mediated
- cisplatin
- dutp
- fadd
- procaspase-3
-
caspase-mediated
-
pan-caspase
-
fas-mediated
-
trail
-
fas-associated
-
trail-induced
-
bcl-2-associated
-
apoptogenic
- pharmacology
- cdc25c
- puma
-
transferase-mediated
-
executioner
-
factor-related
-
deltapsim
- medicine
-
tunel-positive
-
sub-g1
Reaction
strict requirement for an Asp residue at position P1 and with a marked preference for His at position P2. It has a preferred cleavage sequence of Leu-Gly-His-Asp-/-Xaa =
Synonyms
APAF, Apaf-3, apoptotic protease activating factor 3, apoptotic protease Mch-6, C14.010, CASP-9, casp9, casp9-gamma, caspase 9, caspase-9, ICE-LAP6, ICE-like apoptotic protease 6, Mch6
ECTree
Advanced search results
Cloned
Cloned on EC 3.4.22.62 - caspase-9
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
adenovirus expression, AdshRNA-C9 and AdshRNA-eGFP vectors, AdBcl-xL and AdNull adenoviral vectors
B6 splenocytes modified by retroviral transduction, truncated caspase-9 molecule genetically coupled to a modified human FK506-binding protein (FKBPF36V) by generating the iCasp9M-construct, iCasp9M construct (safety switch) and enhanced GFP used for transformation
caspase-9 inactivated by mutation at the catalytic domain, generation of dominant negative caspase-9 overexpressing cell lines, expression in Escherichia coli, follicular lymphoma cells transformed with the lentiviral vector pWPI-IRES-GFP
caspase-9 splice variant Casp9-gamma contains only a caspase recruitment domain and lacks the catalytic domain, expression in 293T cells.Casp9-gamma does not promote apoptosis when overexpressed in 293T cells
expressed in Escherichia coli, pcmyc vector, pFLAG-CTC vector to generate FLAG-tagged caspase-9 construct
expressed in Escherichia coli, recombinant protein, pcDNA3, pET28a, pEGFP vectors
expression of His-tagged wild-type and mutant enzymes in Escherichia coli strain B21(DE3) in incusion bodies
-
gene CSP9, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in Escherichia coli strain BL21(DE3)
-
gene Lyccasp9, DNA and maino acid sequence determination and analysis, full-length cDNA of Lyccasp9 is 2595 bp with an open reading frame of 1314 bp encoding a polypeptide of 437 amino acids, which includes a 90-amino acids caspase recruitment domain (CARD, residues 1-90), a 133-amino acids p20 domain (residues 171-303) with two putative caspase family histidine and cysteine active sites, as well as an 87-amino acids p10 domain (residues 348-435)
-
human caspase-9 (wild type or mutant R10A) are subcloned into the pIND expression plasmid before cotransfection of recombinant pIND and pVgRXR into U2OS cells
-
naturally occuring variant caspase-9S, that is missing most of the large subunit of caspase-9
recombinant expression of His6-tagged holoenzyme in Escherichia coli strain BL21(DE3), recombinantindividual expression of large and small subunits in inclusion bodies
-