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3.4.22.62: caspase-9

This is an abbreviated version!
For detailed information about caspase-9, go to the full flat file.

Word Map on EC 3.4.22.62

Reaction

strict requirement for an Asp residue at position P1 and with a marked preference for His at position P2. It has a preferred cleavage sequence of Leu-Gly-His-Asp-/-Xaa =

Synonyms

APAF, Apaf-3, apoptotic protease activating factor 3, apoptotic protease Mch-6, C14.010, CASP-9, casp9, casp9-gamma, caspase 9, caspase-9, ICE-LAP6, ICE-like apoptotic protease 6, Mch6

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.62 caspase-9

Molecular Weight

Molecular Weight on EC 3.4.22.62 - caspase-9

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30000
x * 30000, caspase 9S, SDS-PAGE
35000
processed caspase-9 protein, SDS-PAGE
37000
processed caspase-9 protein, SDS-PAGE
46200
x * 46200, calculation from nucleotide sequence
47000
un-processed caspase-9 protein, SDS-PAGE
52000
-
pro-caspase-9, Western blot, increased in hypoxic animals
55000
full-length caspase-9, Western blot analysis
68000
observed molecular weight of caspase-9 by tandem mass spectrometry in cell lysates with and without cytochrome c/dATP treatment
69200
calculated molecular weight of caspase-9 by tandem mass spectrometry in cell lysates with and without cytochrome c/dATP treatment