Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | mitochondrial fraction of cerebral tissue | Sus scrofa | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
pro-caspase-9, Western blot, increased in hypoxic animals | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-caspase-3 + H2O | Sus scrofa | modification at Ser196 results in alterations of proteolytic cleavage of procaspase-9 and caspase-9 activity | caspase-3 + ? | - |
? | |
pro-caspase-9 + H2O | Sus scrofa | modification at Ser196 results in alterations of proteolytic cleavage of procaspase-9 and caspase-9 activity | caspase-9 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
newborn piglets, aged 2-5 days | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | phosphorylation on Ser196 in hypoxic animals increased | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortex | mitochondrial fraction of cerebral tissue, hypoxia-treated, classified into a normoxic group and a hypoxic group | Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
increased activity of caspase-9 during hypoxia, significant increase in the phophorylation on Ser196 during hypoxia, modification at Ser196 results in alterations of proteolytic cleavage of procaspase-9 and caspase-9 activity | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-caspase-3 + H2O | modification at Ser196 results in alterations of proteolytic cleavage of procaspase-9 and caspase-9 activity | Sus scrofa | caspase-3 + ? | - |
? | |
pro-caspase-9 + H2O | modification at Ser196 results in alterations of proteolytic cleavage of procaspase-9 and caspase-9 activity | Sus scrofa | caspase-9 | - |
? |