3.4.22.48: staphopain

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For detailed information about staphopain, go to the full flat file.

Word Map on EC 3.4.22.48

3.4.22.48

aureus

staphylococcal

streptococcal

pyogenes

staphostatins

speb

exotoxin

pyrogenic

aureolysin

sspc

gordonii

pharmacology

medicine

Reaction

broad endopeptidase action on proteins including elastin, but rather limited hydrolysis of small-molecule substrates. Assays are conveniently made with hemoglobin, casein or Z-Phe-Arg-NHMec as substrate =

Synonyms

Ecp, extracellular cysteine protease, SCPA, Sscp A, Sscp B, SspB, SspB protein, staphopain, staphopain A, staphopain B, staphopain C, staphylopain

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.48 staphopain

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Results	in table
1	Activating Compound
63	AA Sequence
4	Application
1	CAS Registry Number
18	Cloned(Commentary)
4	Crystallization (Commentary)
2	Expression
8	General Information
36	Inhibitors
8	kcat/KM [mM/s]
4	Ki Value [mM]
13	KM Value [mM]
16	Localization
1	Metals/Ions
4	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
82	Organism
7	pH Optimum
3	Posttranslational Modification
8	Protein Variants
15	Purification (Commentary)
6	Reaction
38	Reference
2	Renatured (Commentary)
11	Source Tissue
8	Specific Activity [micromol/min/mg]
80	Substrates and Products (Substrate)
9	Subunits
53	Synonyms
5	Temperature Optimum [°C]
11	Turnover Number [1/s]

Expression

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Expression on EC 3.4.22.48 - staphopain

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staphopain levels are decreased under biofilm-forming conditions

2 entries