3.4.22.30: Caricain

This is an abbreviated version!
For detailed information about Caricain, go to the full flat file.

Reaction

hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain =

Synonyms

caricain, Chymopapain S, More, Papaya peptidase A, Papaya peptidase II, Papaya proteinase 3, Papaya proteinase A, Papaya proteinase III, Papaya proteinase OMEGA, PPIII, PpOmega, procaricain, Proteinase omega, Proteinase, papaya A, Proteinase, papaya, III

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.30 Caricain

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
1	AA Sequence
3	Application
1	CAS Registry Number
2	Cloned(Commentary)
1	Crystallization (Commentary)
2	General Information
7	Inhibitors
18	KM Value [mM]
2	Localization
7	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
34	Organism
2	PDB ID
7	pH Optimum
1	pH Range
1	pH Stability
1	Posttranslational Modification
4	Protein Variants
9	Purification (Commentary)
7	Reaction
10	Reaction Type
33	Reference
1	Renatured (Commentary)
27	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
41	Substrates and Products (Substrate)
4	Subunits
23	Synonyms
5	Temperature Optimum [°C]
3	Temperature Stability [°C]
8	Turnover Number [1/s]

General Information

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

General Information on EC 3.4.22.30 - Caricain

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to General Information Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

evolution

Carica papaya

P10056

all four major papain-like cysteine proteases (PLCPs) purified from papaya latex, including papain, chymopapain, glycyl endopeptidase and caricain, are grouped into the lineage-specific expansion branch in the subfamily III of papain-like cysteine proteases (PLCPs). Tandem duplications play the dominant role in affecting copy number of PLCPs in plants. Significant variations in size of the PLCP subfamilies among species may reflect genetic adaptation of plant species to different environments. The lineage-specific expansion of papaya PLCPs of subfamily III might have been promoted by the continuous reciprocal selective effects of herbivore attack and plant defense. Phylogenetic analysis, conserved domain identification, gene duplication analysis, and chromosomal distribution of PLCPs, overview

753097

metabolism

Carica papaya

P10056

papain-like cysteine proteases (PLCPs), a large group of cysteine proteases structurally related to papain, play important roles in plant development, senescence, and defense responses

753097