3.4.22.30: Caricain

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For detailed information about Caricain, go to the full flat file.

Reaction

hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain =

Synonyms

caricain, Chymopapain S, More, Papaya peptidase A, Papaya peptidase II, Papaya proteinase 3, Papaya proteinase A, Papaya proteinase III, Papaya proteinase OMEGA, PPIII, PpOmega, procaricain, Proteinase omega, Proteinase, papaya A, Proteinase, papaya, III

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.30 Caricain

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Results	in table
1	Activating Compound
1	AA Sequence
3	Application
1	CAS Registry Number
2	Cloned(Commentary)
1	Crystallization (Commentary)
2	General Information
7	Inhibitors
18	KM Value [mM]
2	Localization
7	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
34	Organism
2	PDB ID
7	pH Optimum
1	pH Range
1	pH Stability
1	Posttranslational Modification
4	Protein Variants
9	Purification (Commentary)
7	Reaction
10	Reaction Type
33	Reference
1	Renatured (Commentary)
27	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
41	Substrates and Products (Substrate)
4	Subunits
23	Synonyms
5	Temperature Optimum [°C]
3	Temperature Stability [°C]
8	Turnover Number [1/s]

Subunits

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Subunits on EC 3.4.22.30 - Caricain

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SUBUNIT

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

?

Carica papaya

-

x * 18800, purified from enzyme solution. Protein lacks the N-terminal 41 residues of enzyme, disulfide bond C22-C63 is opened

670804

monomer

Carica papaya

-

1 * 24000, Carica papaya, SDS-PAGE

30154, 30255

additional information

Carica papaya

-

transition state structure

649880