3.4.22.30: Caricain
This is an abbreviated version!
For detailed information about Caricain, go to the full flat file.
Word Map on EC 3.4.22.30
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3.4.22.30
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proteinases
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latex
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actinidin
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ficin
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catalytic-site
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glycyl
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papain-like
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2,2\'-dipyridyl
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active-centre
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drug development
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food industry
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nutrition
- 3.4.22.30
- proteinases
- latex
- actinidin
- ficin
-
catalytic-site
-
glycyl
-
papain-like
-
2,2\'-dipyridyl
-
active-centre
- drug development
- food industry
- nutrition
Reaction
hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain =
Synonyms
caricain, Chymopapain S, More, Papaya peptidase A, Papaya peptidase II, Papaya proteinase 3, Papaya proteinase A, Papaya proteinase III, Papaya proteinase OMEGA, PPIII, PpOmega, procaricain, Proteinase omega, Proteinase, papaya A, Proteinase, papaya, III
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Application
Application on EC 3.4.22.30 - Caricain
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drug development
caricain would be suitable for enzyme therapy in gluten intolerance and appears to have synergistic action with porcine intestinal extracts, potential for enzyme therapy in coeliac disease
nutrition
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at low pH, enzyme undergoes conformational transition leading to instability and rapid degradation by pepsin. To be effective in gut after oral administration, enzyme needs to be protected against acid denaturation and degradation