3.4.22.30: Caricain

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For detailed information about Caricain, go to the full flat file.

Reaction

hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain =

Synonyms

caricain, Chymopapain S, More, Papaya peptidase A, Papaya peptidase II, Papaya proteinase 3, Papaya proteinase A, Papaya proteinase III, Papaya proteinase OMEGA, PPIII, PpOmega, procaricain, Proteinase omega, Proteinase, papaya A, Proteinase, papaya, III

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.30 Caricain

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Results	in table
1	Activating Compound
1	AA Sequence
3	Application
1	CAS Registry Number
2	Cloned(Commentary)
1	Crystallization (Commentary)
2	General Information
7	Inhibitors
18	KM Value [mM]
2	Localization
7	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
34	Organism
2	PDB ID
7	pH Optimum
1	pH Range
1	pH Stability
1	Posttranslational Modification
4	Protein Variants
9	Purification (Commentary)
7	Reaction
10	Reaction Type
33	Reference
1	Renatured (Commentary)
27	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
41	Substrates and Products (Substrate)
4	Subunits
23	Synonyms
5	Temperature Optimum [°C]
3	Temperature Stability [°C]
8	Turnover Number [1/s]

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

D158N

2 entries

E50A

Carica papaya

P10056

site-directed mutagenesis, reduced activity at pH 6.8

651250

E50A/D158N

Carica papaya

P10056

site-directed mutagenesis, reduced activity at pH 6.8

651250

D158N

Carica papaya

-

altered ionization kinetics required for catalysis

649808

D158N

Carica papaya

P10056

site-directed mutagenesis, reduced activity at pH 6.8

651250