3.4.21.B43: kallikrein 12

This is an abbreviated version!
For detailed information about kallikrein 12, go to the full flat file.

Reaction

proteolytic cleavage of polypeptides =

Synonyms

hK12, K12, kallikrein 12, kallikrein-related peptidase 12, KLK12, S01.020

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B43 kallikrein 12

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
1	AA Sequence
3	Application
2	CAS Registry Number
5	Cloned(Commentary)
101	Disease/ Diagnostics
3	Expression
11	General Information
2	IC50 Value
12	Inhibitors
7	KM Value [mM]
1	Localization
3	Metals/Ions
4	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
16	Organism
5	pH Optimum
1	pH Stability
1	Posttranslational Modification
2	Purification (Commentary)
2	Reaction
2	Reaction Type
16	Reference
52	Source Tissue
2	Storage Stability
35	Substrates and Products (Substrate)
1	Subunits
23	Synonyms
4	Temperature Optimum [°C]
10	Turnover Number [1/s]

pH Stability

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

pH Stability on EC 3.4.21.B43 - kallikrein 12

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to pH Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

pH STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5 - 7

Homo sapiens

-

when the pH is decreased to less than 5.0, KLK12 enzyme activity becomes undetectable, KLK12 activity is very sensitive to pH changes in the range 6.5-7.0 (within this range, a decrease of 0.5 pH units results in a more than 60% reduction in activity)

678534