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3.4.21.B43: kallikrein 12

This is an abbreviated version!
For detailed information about kallikrein 12, go to the full flat file.

Word Map on EC 3.4.21.B43

Reaction

proteolytic cleavage of polypeptides =

Synonyms

hK12, K12, kallikrein 12, kallikrein-related peptidase 12, KLK12, S01.020

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.B43 kallikrein 12

Expression

Expression on EC 3.4.21.B43 - kallikrein 12

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
Expression of both KLK12 and PDGFB genes is regulated by hypoxia in the lung tumor microenvironment
KLK12 expression is increased in lung tumor
upregulation of KLK12 in Mycobacterium bovis infected murine macrophages plays a substantial role in the protective immune response regulation by modulating autophagy, apoptosis and pro-inflammatory pathways
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