3.4.21.B43: kallikrein 12

This is an abbreviated version!
For detailed information about kallikrein 12, go to the full flat file.

proteolytic cleavage of polypeptides =

hK12, K12, kallikrein 12, kallikrein-related peptidase 12, KLK12, S01.020

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Results	in table
1	Activating Compound
1	AA Sequence
3	Application
2	CAS Registry Number
5	Cloned(Commentary)
101	Disease/ Diagnostics
3	Expression
11	General Information
2	IC50 Value
12	Inhibitors
7	KM Value [mM]
1	Localization
3	Metals/Ions
4	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
16	Organism
5	pH Optimum
1	pH Stability
1	Posttranslational Modification
2	Purification (Commentary)
2	Reaction
2	Reaction Type
16	Reference
52	Source Tissue
2	Storage Stability
35	Substrates and Products (Substrate)
1	Subunits
23	Synonyms
4	Temperature Optimum [°C]
10	Turnover Number [1/s]

Storage Stability on EC 3.4.21.B43 - kallikrein 12

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37°C, 12.5 mM MES, 75 mM NaCl, after 16 h, 24 h, 48 h, and 72 h only 50%, 35%, 20%, and 10% of the initial activity is detected

37°C, in the presence of 10-20% glycerol and 0.05% Brij-35, 72 h, 10% loss of activity