3.4.21.B4: granzyme K

This is an abbreviated version!
For detailed information about granzyme K, go to the full flat file.

endopeptidase activity. Cleaves after Lys and Arg =

fragmentin, Gr3, granzyme 3, granzyme K, granzyme tryptase K, GRK, grzK, Gzm K, GzmK, lymphocyte tryptase 2, RNK-Tryp-2, S01.146, tryptase

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Results	in table
3	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
1	Crystallization (Commentary)
59	Disease/ Diagnostics
1	Expression
9	General Information
1	General Stability
52	Inhibitors
7	Ki Value [mM]
4	KM Value [mM]
3	Localization
7	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
30	Organism
5	pH Optimum
2	pI Value
1	Posttranslational Modification
4	Protein Variants
9	Purification (Commentary)
1	Reaction
23	Reaction Type
30	Reference
36	Source Tissue
5	Specific Activity [micromol/min/mg]
51	Substrates and Products (Substrate)
1	Subunits
33	Synonyms

Natural Substrates Products on EC 3.4.21.B4 - granzyme K

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Protein + H2O

redox factor-1/apurinic apyrimidinic endonuclease Ape1 + H2O

Ape1 cleavage by Granzyme K facilitates intracellular reactive oxygen species accumulation and enhances granzyme K-induced cell death

additional information