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Literature summary for 3.4.21.B4 extracted from

  • Hink-Schauer, C.; Estebanez-Perpina, E.; Wilharm, E.; Fuentes-Prior, P.; Klinkert, W.; Bode, W.; Jenne, D.E.
    The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features (2002), J. Biol. Chem., 277, 50923-50933.
    View publication on PubMed
Search for more literature for 3.4.21.B4

Cloned(Commentary)

Cloned (Comment) Organism
S195A variant expressed in Escherichia coli Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method Homo sapiens

Protein Variants

Protein Variants Comment Organism
S195A more stable but otherwise identical to wild-type enzyme Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens can trigger DNA fragmentation and is involved in apoptosis ?
-
 ?
Protein + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information can trigger DNA fragmentation and is involved in apoptosis Homo sapiens ?
-
 ?
Protein + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
GzmK
-
 Homo sapiens