3.4.21.B4: granzyme K
This is an abbreviated version!
For detailed information about granzyme K, go to the full flat file.
Word Map on EC 3.4.21.B4
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3.4.21.B4
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perforin
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spastic
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paraplegia
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oxysterols
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neurosteroids
- 3.4.21.B4
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perforin
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spastic
-
paraplegia
-
oxysterols
-
neurosteroids
Reaction
endopeptidase activity. Cleaves after Lys and Arg =
Synonyms
fragmentin, Gr3, granzyme 3, granzyme K, granzyme tryptase K, GRK, grzK, Gzm K, GzmK, lymphocyte tryptase 2, RNK-Tryp-2, S01.146, tryptase
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Purification
Purification on EC 3.4.21.B4 - granzyme K
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DE52 anion-exchange column chromatography, Q Sepharose column chromatography, hydroxylapatite column chromatography, and Sephadex G-75 gel filtration
recombinant wild-type and mutant enzymes by cation-exchange chromatography and affinity chromatography on Prot A/G beads, followed by dialysis