3.4.17.12: carboxypeptidase M

This is an abbreviated version!
For detailed information about carboxypeptidase M, go to the full flat file.

cleavage of C-terminal arginine or lysine residues from polypeptides =

carboxypeptidase M, carboxypeptidase-M, CPM, M14006 (Merops-ID), More

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Results	in table
7	Activating Compound
27	AA Sequence
8	Application
1	CAS Registry Number
11	Cloned(Commentary)
2	Crystallization (Commentary)
3463	Disease/ Diagnostics
1	Expression
2	General Information
31	Inhibitors
2	Ki Value [mM]
52	KM Value [mM]
32	Localization
14	Metals/Ions
13	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
32	Organism
1	PDB ID
9	pH Optimum
3	pH Range
3	pH Stability
17	Posttranslational Modification
7	Protein Variants
9	Purification (Commentary)
3	Reaction
13	Reaction Type
32	Reference
118	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
74	Substrates and Products (Substrate)
9	Subunits
35	Synonyms
3	Temperature Optimum [°C]
5	Temperature Stability [°C]
52	Turnover Number [1/s]

Activating Compound on EC 3.4.17.12 - carboxypeptidase M

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G-CSF

granulocyte-colony stimulating factor

IFN-gamma

CPM activity can be upregulated approximately two-fold in HLMVECs by IL-1beta plus IFN-gamma treatment

IL-1beta

CPM activity can be upregulated approximately two-fold in HLMVECs by IL-1beta plus IFN-gamma treatment, IL-1beta alone can upregulate CPM expression

lipopolysaccharide

following stimulation with bacterial lipopolysaccharide a marginal upregulation of the expression of carboxypeptidase M is observed

additional information