3.4.17.12: carboxypeptidase M
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For detailed information about carboxypeptidase M, go to the full flat file.
Word Map on EC 3.4.17.12
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3.4.17.12
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pain
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women
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lymphocyte
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contralateral
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children
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postoperative
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prophylactic
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myelinolysis
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mastectomy
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pontine
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knee
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cyclophosphamide
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unilateral
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wave
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rehabilitation
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hyponatremia
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decision
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summation
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session
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flexion
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accelerometer
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myoelectrical
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chlorpheniramine
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preoperative
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arthroplasty
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noxious
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phytohemagglutinin
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3h-thymidine
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maleate
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pressor
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pain-free
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decision-making
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analgesia
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psychophysical
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actigraph
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pokeweed
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moderate-to-vigorous
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3h-tdr
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disomy
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myotomy
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cuff
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physiotherapy
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arthroscopic
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gastroparesis
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suprathreshold
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dysrhythmias
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breast-conserving
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medicine
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trapezius
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manometry
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resting-state
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diagnostics
- 3.4.17.12
- pain
- women
- lymphocyte
-
contralateral
- children
-
postoperative
-
prophylactic
- myelinolysis
-
mastectomy
- pontine
- knee
- cyclophosphamide
-
unilateral
-
wave
-
rehabilitation
- hyponatremia
-
decision
-
summation
-
session
-
flexion
-
accelerometer
-
myoelectrical
-
chlorpheniramine
-
preoperative
-
arthroplasty
-
noxious
- phytohemagglutinin
-
3h-thymidine
- maleate
-
pressor
-
pain-free
-
decision-making
-
analgesia
-
psychophysical
-
actigraph
-
pokeweed
-
moderate-to-vigorous
-
3h-tdr
-
disomy
-
myotomy
-
cuff
-
physiotherapy
-
arthroscopic
-
gastroparesis
-
suprathreshold
- dysrhythmias
-
breast-conserving
- medicine
-
trapezius
-
manometry
-
resting-state
- diagnostics
Reaction
cleavage of C-terminal arginine or lysine residues from polypeptides =
Synonyms
carboxypeptidase M, carboxypeptidase-M, CPM, M14006 (Merops-ID), More
ECTree
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Application
Application on EC 3.4.17.12 - carboxypeptidase M
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diagnostics
medicine
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CPM, a gene that encodes carboxypeptidase M, is consistently amplified in liposarcomas but not in different subtypes of lipoma or normal fat, CPM could be used as an alternative and novel diagnostic tool for these tumors
diagnostics
expression is positively correlated with overall survival and negatively correlated with recurrence, lymph node invasion, and N stage in colorectal cancer
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CPM might be an important target for the development of new drugs to treat inflammatory diseases and cancer
medicine
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the present data could lead to improved IHC tests in lung adenocarcinomas when the prognostic value of EGFR expression needs to be evaluated for a target therapy especially when EGFR gene exhibited to mutations
medicine
patients with chronic persistent atrial fibrillation have reduced amounts of CPM mRNA and protein in the atrial tissue
medicine
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tumor cells of renal cell carcinoma subtypes lose carboxypeptidase M expression upon dedifferentiation. There is a correlation between low carboxypeptidase M expression and tumor cell type. Carboxypeptidase M staining is intense on phagocytotic tumor-associated macrophages, and enzyme is also detected in the tumor-associated vasculature. Coexistence of carboxypeptidase M and the epidermal growth factor receptor is detected in papillary renal cell carcinoma
medicine
expression is positively correlated with overall survival and negatively correlated with recurrence, lymph node invasion, and N stage in colorectal cancer
medicine
the rs12812500 variant of the carboxypeptidase M gene may increase silicosis susceptibility by affecting the expression of carboxypeptidase M, which may contribute to silicosis susceptibility with biological plausibility