3.2.2.7: adenosine nucleosidase
This is an abbreviated version!
For detailed information about adenosine nucleosidase, go to the full flat file.
Word Map on EC 3.2.2.7
-
3.2.2.7
-
purine
-
nucleoside
-
salvage
-
riboside
-
inosine
-
lupinus
-
luteus
-
8-14cadenosine
-
3.3.1.1
-
s-adenosyl-l-homocysteine
- 3.2.2.7
- purine
- nucleoside
-
salvage
- riboside
- inosine
-
lupinus
- luteus
-
8-14cadenosine
-
3.3.1.1
- s-adenosyl-l-homocysteine
Reaction
Synonyms
adenosinase, adenosine hydrolase, ANase, N-ribosyladenine ribohydrolase
ECTree
3.2.2.7 adenosine nucleosidaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 3.2.2.7 - adenosine nucleosidase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3'-deoxyadenosine + H2O
6-aminopurine + 3-deoxy-D-ribofuranose
-
6-aminopurine-9-3'-deoxy-beta-D-ribofuranoside, cordycepin, very low activity
-
?
5'-deoxyadenosine + H2O
6-aminopurine + 5-deoxy-D-ribofuranose
-
6-aminopurine-9-5'-deoxy-beta-D-ribofuranoside, best substrate
-
?
6-aminopurine-9-beta-D-ribofuranosyl-N1-oxide + H2O
6-aminopurine-N1-oxide + D-ribofuranose
6-benzylaminopurine riboside + H2O
6-benzylaminopurine + D-ribose
-
low activity
-
?
7-methyl-6-aminopurine-9-beta-D-ribofuranoside + H2O
7-methyl-6-aminopurine + D-ribofuranose
-
5fold faster hydrolysis compared to adenosine
-
?
guanosine + H2O
2-amino-1,9-dihydropurine-6-on + D-ribofuranose
-
2-amino-1,9-dihydro-6-oxopurine-9-beta-D-ribofuranoside, two third lowered activity compared to adenosine as substrate
-
?
N6-(DELTA2-isopentenyl)-adenosine + H2O
N6-(DELTA2-isopentenyl)-6-aminopurine + D-ribofuranose
-
N6-(DELTA2-isopentenyl)-6-aminopurine-9-beta-D-ribofuranoside
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
hydrolysis at the same rate as for adenosine
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
6-aminopurine-9-2'-deoxy-beta-D-ribofuranoside
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
3-4 times greater hydrolysis compared to adenosine
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
6-aminopurine-9-2'-deoxy-beta-D-ribofuranoside
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
hydrolyzes at 96% of the rate of adenosine
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
6-aminopurine-9-2'-deoxy-beta-D-ribofuranoside
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
6-aminopurine-9-2'-deoxy-beta-D-ribofuranoside
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
one third lowered activity compared to adenosine as substrate
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
6-aminopurine-9-2'-deoxy-beta-D-ribofuranoside
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
hydrolysis at the same rate as for adenosine
-
?
2'-deoxyadenosine + H2O
6-aminopurine + 2-deoxy-D-ribofuranose
-
6-aminopurine-9-2'-deoxy-beta-D-ribofuranoside
-
?
6-aminopurine-9-beta-D-ribofuranosyl-N1-oxide + H2O
6-aminopurine-N1-oxide + D-ribofuranose
-
rapid hydrolysis
-
?
6-aminopurine-9-beta-D-ribofuranosyl-N1-oxide + H2O
6-aminopurine-N1-oxide + D-ribofuranose
-
same hydrolysis rate than for adenosine or 2'-deoxyadenosine
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
component of the purine salvage pathway
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
component of the purine salvage pathway
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
component of the purine salvage pathway
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
component of the purine salvage pathway
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
involved in maintaining an active pool of S-adenosyl-L-methionine for transmethylation reactions
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
component of the purine salvage pathway
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
implicated in metabolism of cytokinins
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
adenosine + H2O
6-aminopurine + D-ribofuranose
-
implicated in metabolism of cytokinins
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
component of the purine salvage pathway
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
-
6-aminopurine-9-beta-D-ribofuranoside
-
?
adenosine + H2O
6-aminopurine + D-ribofuranose
Ulmus carpinifolia
-
6-aminopurine-9-beta-D-ribofuranoside
-
ir
inosine + H2O
hypoxanthine + D-ribose
-
9-ribosylhydroxanthine, low activity
-
?
additional information
?
-
-
the pure recombinant protein exhibits highest hydrolase activity for uridine, followed by inosine and adenosine
-
-
?
additional information
?
-
-
56-92% of adenosine taken up by leaf disks may be converted to salvage products, efficient adenosine salvage abilitiy in mangrove is coupled to high enzymic activity and is stimulated by salt, proposed metabolic pathway
-
-
?
additional information
?
-
-
56-92% of adenosine taken up by leaf disks may be converted to salvage products, efficient adenosine salvage abilitiy in mangrove is coupled to high enzymic activity and is stimulated by salt, proposed metabolic pathway
-
-
?
additional information
?
-
-
proposed pathway for biosynthesis of purine alkaloids with adenosine derived from SAM cycle
-
-
?
additional information
?
-
-
56-92% of adenosine taken up by leaf disks may be converted to salvage products, efficient adenosine salvage abilitiy in mangrove is coupled to high enzymic activity and is stimulated by salt, proposed metabolic pathway
-
-
?
additional information
?
-
-
30% of adenosine taken up by leaf disks may be converted to salvage products
-
-
?
additional information
?
-
-
30% of adenosine taken up by leaf disks is hydrolysed to adenine
-
-
?
additional information
?
-
-
all of the ribonucleosides tested are better substrates than their corresponding 2'-deoxynucleosides. The purines are better substrates than the pyrimidines
-
-
?
additional information
?
-
-
56-92% of adenosine taken up by leaf disks may be converted to salvage products, efficient adenosine salvage abilitiy in mangrove is coupled to high enzymic activity and is stimulated by salt, proposed metabolic pathway
-
-
?
additional information
?
-
-
56-92% of adenosine taken up by leaf disks may be converted to salvage products, efficient adenosine salvage abilitiy in mangrove is coupled to high enzymic activity and is stimulated by salt, proposed metabolic pathway
-
-
?
