2.1.1.41: sterol 24-C-methyltransferase

This is an abbreviated version!
For detailed information about sterol 24-C-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.41

2.1.1.41

ergosterol

leishmaniasis

lanosterol

infantum

medicine

tomatidine

24-alkyl

drug development

24-ethyl

c24-methylation

agriculture

c1-transfer

degradation

Reaction

24-methylene-5alpha-cholest-8-en-3beta-ol

Synonyms

(S)-adenosyl-L-methionine:DELTA24(25)-sterol methyl transferase, 24-C-sterol methyltransferase, 24-SMT, 24-sterol C-methyltransferase, C-24 sterol methyltransferase, C24-methyltransferase, DELTA(24,25)-SMT, DELTA24-methyltransferase, DELTA24-sterol methyltransferase, Erg6, Erg6p, LMJF_36_2380, LMJF_36_2390, methyltransferase, DELTA24-sterol, PbSMT, phytosterol methyltransferase, S-adenosyl-4-methionine:sterol DELTA24-methyltransferase, S-adenosyl-L-methionine:DELTA24(23)-sterol methyltransferase, SAM:SMT, SMT, SMT protein, SMT1, SMT80, SMT90, sterol 24-C-methyltransferase, sterol C24-methyltransferase, sterol methyltransferase, STM, TbSMT, zymosterol 24-methyltransferase, zymosterol-24-methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.41 sterol 24-C-methyltransferase

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Results	in table
6	Activating Compound
191	AA Sequence
12	Application
1	CAS Registry Number
15	Cloned(Commentary)
5	Cofactor
5	General Information
1	General Stability
8	IC50 Value
106	Inhibitors
6	kcat/KM [mM/s]
64	Ki Value [mM]
59	KM Value [mM]
12	Localization
2	Metals/Ions
8	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
52	Organism
6	Pathway
15	pH Optimum
7	pH Range
205	Protein Variants
17	Purification (Commentary)
18	Reaction
1	Reaction Type
47	Reference
5	Source Tissue
13	Specific Activity [micromol/min/mg]
2	Storage Stability
114	Substrates and Products (Substrate)
6	Subunits
82	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
2	Temperature Range [°C]
36	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.1.1.41 - sterol 24-C-methyltransferase

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0.0035

22,26-azasterol

Leishmania major

688896

0.005

24(R,S),25-epiminolanosterol

Candida albicans

pH 7.5, 30°C

718692

0.02

24-thialanosterol

Candida albicans

pH 7.5, 30°C

718692

0.000014 - 0.003

25-azalanosterol

2 entries

0.00176 - 0.00243

azasterol

2 entries

0.00383

ketoconazole

Leishmania major

688896