1.1.1.B52: 3-quinuclidinone reductase (NADH)

This is an abbreviated version, for detailed information about 3-quinuclidinone reductase (NADH), go to the full flat file.

Reaction

(R)-3-quinuclidinol
+
NAD+
=
3-quinuclidinone
+
NADH
+
H+

Synonyms

alcohol dehydrogenase, ArQR, AtQR, BacC, QNR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B52 3-quinuclidinone reductase (NADH)

Crystallization

Crystallization on EC 1.1.1.B52 - 3-quinuclidinone reductase (NADH)

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Crystallization/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
crystallized under a reservoir solution condition of 0.2 M ammonium acetate, 0.1 M HEPES pH 8.5 and 24% (w/v) PEG3350
-
sitting-drop vapour-diffusion method at 20°C. Crystals are obtained using a reservoir solution containing PEG 3350 as a precipitant. X-ray diffraction data are collected to 1.72 A resolution. The crystal belongs to space group P2(1), with unit-cell parameters a = 62.0, b = 126.4, c = 62.0 A, beta = 110.5, and is suggested to contain four molecules in the asymmetric unit
-