1.1.1.75: (R)-aminopropanol dehydrogenase

This is an abbreviated version, for detailed information about (R)-aminopropanol dehydrogenase, go to the full flat file.

Reaction

(R)-1-Aminopropan-2-ol
+
NAD+
=
aminoacetone
+
NADH
+
H+

Synonyms

1-aminopropan-2-ol-dehydrogenase, 1-aminopropan-2-ol-NAD+ dehydrogenase, AADH, DL-1-aminopropan-2-ol: NAD+ dehydrogenase, L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase, L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase, L-1-amino-2-propanol dehydrogenase, L-aminopropanol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.75 (R)-aminopropanol dehydrogenase

pH Range

pH Range on EC 1.1.1.75 - (R)-aminopropanol dehydrogenase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.5 - 8
-
washed cell suspension, very low activity at 4.5, 50% activity at pH 8
6 - 10
-
two peaks at pH 7 and 10 with very low activity at pH 8.5, at pH 7 50% of maximum activity
6 - 10.5
-
low activity at pH 6, 80% of activity at pH 10.5
6.5 - 9
-
cell free extracts, 50% activity at both pH
7.5 - 11
-
very low activity at pH 7.5, 60% of activity at pH 11 in liver homogenates
8.5 - 10.5
-
40% of activity in soluble extract of disintegrated mitochondria