1.1.1.75: (R)-aminopropanol dehydrogenase

This is an abbreviated version, for detailed information about (R)-aminopropanol dehydrogenase, go to the full flat file.

Reaction

(R)-1-Aminopropan-2-ol
+
NAD+
=
aminoacetone
+
NADH
+
H+

Synonyms

1-aminopropan-2-ol-dehydrogenase, 1-aminopropan-2-ol-NAD+ dehydrogenase, AADH, DL-1-aminopropan-2-ol: NAD+ dehydrogenase, L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase, L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase, L-1-amino-2-propanol dehydrogenase, L-aminopropanol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.75 (R)-aminopropanol dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.75 - (R)-aminopropanol dehydrogenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
-
3-chloromercuribenzoate
-
complete inhibition at 0.05 mM
8-hydroxyquinoline
-
nearly complete inhibition at 2.5 mM
D,L-1,3-diaminopropan-2-ol
-
-
D,L-1-bromopropan-2-ol
-
-
D,L-1-chloropropan-2-ol
-
-
D,L-2hydroxy-2-phenylethylamine
D,L-3-hydroxybutyrate
D,L-propan-1,2-diol
-
-
D,L-serine
-
-
D-1-amininopropan-2-ol
-
EDTA
-
weak inhibition at high concentration, little effect in soluble extract of disintegrated mitochondria
iodoacetate
-
more inhibitory in intact cells than in cell free extracts
L-1-(3,4-dihydroxyphenyl)-2-aminoethanol
-
noradrenalin
L-cysteine
-
-
sodium carbonate/dicarbonate buffers
-
at alkaline pH
-