EC Number   |
Protein Variants |
Reference  |
|---|
   7.4.2.5 | more |
large in-frame deletion of SpaT, not translocation is interrupted, but proteolytic cleavage of the leader segment while the precurser resides in the cell wall |
-, 210373 |
| 7.4.2.5 | G55A |
mutation in the potential ATP-binding site in ExeA, decreased rate of aerolysin secretion |
210378 |
| 7.4.2.5 | G55D |
mutation in the potential ATP-binding site in ExeA, decreased rate of aerolysin secretion |
210378 |
| 7.4.2.5 | G55V |
mutation in the potential ATP-binding site in ExeA, decreased rate of aerolysin secretion |
210378 |
| 7.4.2.5 | E599Q |
3000fold reduction of ATPase activity compared to wild-type |
656145 |
| 7.4.2.5 | more |
mutant pairs of TAP1/TAP2 with mutation in ABC signature motif, C-loop. Chimera with two canonical C-loops show highest transport activity, chimera with two degenerate C-loops have lowest transport rates. All single mutants and chimera show similar activities in peptide or ATP binding |
656253 |
| 7.4.2.5 | D630M |
ATPase activity is 0.6% of wild-type activity |
-, 667495 |
| 7.4.2.5 | K508M |
ATPase activity is 1.3% of wild-type activity |
-, 667495 |
| 7.4.2.5 | P624C |
insoluble mutant protein |
667495 |
| 7.4.2.5 | P624L |
insoluble mutant protein |
-, 667495 |
