EC Number   |
Cofactor |
Reference |
|---|
    4.2.1.22 | heme |
- |
649869, 649888, 649914, 650105, 650154, 652551, 652695, 681230, 697850, 698157, 701064, 701929, 704974, 713958, 714071, 715172, 729799 |
| 4.2.1.22 | pyridoxal 5'-phosphate |
- |
649869, 649914, 650096, 650105, 650154, 652551, 652695, 664020, 682076, 686517, 687896, 696253, 696822, 697295, 697850, 698157, 698182, 701064, 701750, 701929, 702107, 702457, 704177, 704974, 705345, 706024, 706620, 714071, 714179, 714248, 714912, 715150, 715172, 715808, 715809, 716763 |
| 4.2.1.22 | S-adenosyl-L-methionine |
- |
5604, 704974 |
| 4.2.1.22 | heme |
2 mol per mol of tetrameric enzyme |
5601, 5602 |
| 4.2.1.22 | pyridoxal 5'-phosphate |
2 mol per mol of tetrameric enzyme |
5601 |
| 4.2.1.22 | pyridoxal 5'-phosphate |
4 pyridoxal phosphate molecules per tetramer |
649888 |
| 4.2.1.22 | S-adenosyl-L-methionine |
activation |
5599 |
| 4.2.1.22 | S-adenosyl-L-methionine |
allosterical regulation, increase of the enzyme's affinity for homocysteine |
5600 |
| 4.2.1.22 | heme |
b-type heme |
650096 |
| 4.2.1.22 | heme |
carbon monoxide or nitric oxide can bind to the cofactor, resulting in enzyme inhibition |
680641 |
