EC Number   |
Subunits |
Reference |
|---|
   3.1.4.39 | ? |
domains discovered are adjacent somatomedin B-like domain, nuclease-like domain and a single EF hand-like motif, modulator of oligodendrocyte remodeling and focal adhesion organization (MORFO) domain is located at the C-terminal end of the protein and entails the nuclease-like domain not thought to be catalytically active and functions independently of ATX's enzymatic activity |
696397 |
| 3.1.4.39 | ? |
x * 33000 |
731004 |
| 3.1.4.39 | ? |
x * 35000, SDS-PAGE |
714107 |
| 3.1.4.39 | ? |
x * 37000, SDS-PAGE |
751053 |
| 3.1.4.39 | monomer |
- |
678393, 715637 |
| 3.1.4.39 | More |
ATX has several distinct domains. At the N-terminus it harbours two consecutive cysteine-rich somatomedin-B-like, SMB, domains, a fold known to be involved in protein-protein interactions. The central catalytic phosphodiesterase, PDE, domain follows the SMB domains. At its C-terminus, ATX contains a nuclease-like, NUC, domain, which is catalytically inert and might be involved in substrate binding and presentation |
716315 |
| 3.1.4.39 | More |
ATX is a multi-domain protein encompassing two N-terminal somatomedin B-like domains, a central catalytic phosphodiesterase domain and a C-terminal nuclease-like domain |
713629 |
| 3.1.4.39 | More |
autotaxin domain arrangement and structure, overview |
716316 |
| 3.1.4.39 | More |
domain structure of the major ATX isoforms, overview |
730155 |
| 3.1.4.39 | More |
single polypeptide with an N-terminal putative transmembrane domain, which may also function as a signal sequence specifying secretion of the protein |
681769 |
