EC Number   |
General Information |
Reference |
|---|
    1.11.1.9 | malfunction |
disruption of the enzyme (OsGPX5) via T-DNA insertion has adverse effects on the normal development of rice. The OsGPX5 mutant line exhibits lower germination potential, shorter length of 6-day-old seedlings, and a smaller number of filled grains compared to wild-type plants. The seedlings of OsGPX5 mutant plants exhibit enhanced sensitivity to salt stress |
758029 |
| 1.11.1.9 | malfunction |
methylmercury neurotoxicity is associated with inhibition of glutathione peroxidase |
712067 |
| 1.11.1.9 | metabolism |
organoselenium compounds such as substituted salicyloyl 5-seleninic acids may act as possible GPx mimics. For active compounds to be reduced by glutathione reductase, Root Mean Square Distances representing 3 interatomic distances (Sligand-SCys-58, Sligand-NHis-467 and Seligand-NHis-467) necessary for the catalytic interaction with glutathione reductase are below 4.7A and docking scores are within 74-81 Kcal/mol |
765202 |
| 1.11.1.9 | metabolism |
presence of 5% O2 improves the glutathione peroxidase activity, p110-PI3K/Thr308-Akt pathway and differentiation while 1% O2 decreases all these parameters compared to 21% O2. N-acetylcysteine (0.5 mM) can prevent the deleterious effects of hypoxia (1% O2) on the L6 myoblast proliferation and enhances the myoblast differentiation when exposed to 21% O2 |
742248 |
| 1.11.1.9 | physiological function |
anti-oxidant enzyme, essential for cell survival during oxidative stress |
702092 |
| 1.11.1.9 | physiological function |
beyond being an efficient ROS and peroxide scavenger, the enzyme (OsGPX5) participates in the interaction between ER stress and redox homeostasis, which is essential for the normal development of rice under stress conditions |
758029 |
| 1.11.1.9 | physiological function |
characterizion of glutathione peroxidase isoforms in the symbiotic cnidarian Anemonia viridis. TheGPx repertoire shows 7 GPx transcripts belonging to the Anemonia viridis host and 4 GPx transcripts strongly related to Symbiodinium sp. |
742015 |
| 1.11.1.9 | physiological function |
compound shows glutathione peroxidase-like activity |
764281 |
| 1.11.1.9 | physiological function |
glutathione peroxidase activity increases in the brain of mice treated with a derivative of acetaldehyde ammonia during long-term intermittent normobaric hypoxia |
764392 |
| 1.11.1.9 | physiological function |
glutathione peroxidase-3 is a key antioxidant enzyme in the plasma. Endothelial cell-derived GPx-3 protects the vasculature from oxidative stress |
712065 |
