EC Number   |
General Information  |
Reference |
|---|
    1.1.1.267 | metabolism |
1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) is a rate-limiting enzyme that transforms 1-deoxy-D-xylulose 5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) and controls flux through the MEP pathway. Relationship between SaDXR and the biosynthesis of chlorophylls, carotenoids, and sandalwood-specific sesquiterpenoids, overview |
763120 |
| 1.1.1.267 | metabolism |
1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), an important enzyme in the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway in plant plastids, provides the basic five-carbon units for isoprenoid biosynthesis. Roles of the MEP pathway in regulating growth, development, and artemisinin biosynthesis of Artemisia annua |
763576 |
| 1.1.1.267 | metabolism |
1-deoxy-D-xylulose-5-phosphate synthase (DXS) and 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) are key enzymes in terpenoid biosynthesis. The first two rate-limiting enzymes in the plastid-located 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway are 1-deoxy-D-xylulose-5-phosphate synthase (DXS) and 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). The first major step involves DXS-dependent catalysis of pyruvate and D-glyceraldehyde-3-phosphate to form 1-deoxy-D-xylulose-5-phosphate (DXP). The second step is catalyzed by DXR and generates MEP, followed by several enzymatic reactions to produce precursors of IPP and DMAPP. DXS catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate (DXP) from pyruvate and D-glyceraldehyde-3-phosphate. DXR catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate (MEP) from DXP |
763591 |
| 1.1.1.267 | metabolism |
1-deoxy-D-xylulose-5-phosphate, DXP, reductoisomerase catalyzes the first committed step in the 2-C-methyl-D-erythritol 4-phosphate pathway involving a skeletal rearrangement of DXP via a retroaldol/aldol process followed by reduction by NADPH to yield 2-C-methyl-D-erythritol 4-phosphate |
724374 |
| 1.1.1.267 | metabolism |
induction of DXR expression causes increased thymol and carvacrol production |
748373 |
| 1.1.1.267 | metabolism |
organ-specific differential roles of rice Deoxyxylulose 5-phosphate synthase (DXS) and deoxyxylulose 5-phosphate reductoisomerase (DXR), the first two enzymes of the methylerythritol 4-phosphate (MEP) pathway, in carotenoid metabolism in Oryza sativa leaves and seeds. DXS and DXR are the enzymes that catalyze the first two enzyme steps of the MEP pathway to supply the isoprene building-blocks of carotenoids. Enzyme OsDXS2 functions as a rate-limiting enzyme supplying IPP/DMAPPs to seed carotenoid metabolism, but OsDXR does not in either leaves or seeds. Carotenoid and MEP pathway regulation, overview |
762871 |
| 1.1.1.267 | metabolism |
rate-limiting enzyme in the 2-methyl-D-erythritol-4-phosphate (MEP) terpenoid biosynthetic pathway catalyzing the second step |
763482 |
| 1.1.1.267 | metabolism |
the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) is the rate-limiting enzyme in the methylerythritol 4-phosphate pathway (MEP) via conversion of 1-deoxy-D-xylulose-5-phosphate (DXP) into MEP |
762525 |
| 1.1.1.267 | metabolism |
the 1-deoxy-D-xylulose-5-phosphate reductoisomerase is the second enzyme in the nonmevalonate isoprene biosynthesis pathway, catalyzing the reductive isomerization of 1-deoxy-D-xylulose-5-phosphate to 2-methyl-D-erythritol-4-phosphate for making isopentenyl diphosphate and dimethylallyl diphosphate |
723812 |
| 1.1.1.267 | metabolism |
the enzyme catalyzes the first comitted step in the methyl erythritol phosphate (MEP) pathway |
-, 760333 |
