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EC Number General Information Commentary Reference
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267evolution Dioscorea zingiberensis DzDXR is highly homologous to other plant DXRs, especially to those in monocotyledons 762782
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267physiological function DXR is essential for the survival of multiple pathogenic bacteria/parasites 763000
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267physiological function DXR is essential for the survival of multiple pathogenic bacteria/parasites, including those that cause tuberculosis and malaria in humans -, 763000
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267malfunction DXR is essential for the survival of the pathogen, and its inhibition leads to the antimalarial action 763000
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267malfunction DXR is essential for the survival of the pathogen, and its inhibition leads to the antitubercular action -, 763000
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267more enzyme active site structure analysis -, 762747
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267more enzyme CaDXR contains three conserved domain, namely NADPH (GSTGSIGT and LAAGSNV), substrate binding (LPADSEHSAI and NKGLEVIEAHY) and Cys-Ser-(Ala/Met/Val/Thr) cleavage-site domains. Three-dimensional molecular modeling and model validation, and molecular dynamics simulation of modeled DXR, overview 762525
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267physiological function enzyme OsDXS2 functions as a rate-limiting enzyme supplying IPP/DMAPPs to seed carotenoid metabolism, but OsDXR does not in either leaves or seeds. DXR plays essential roles in the development and survival of plants. No positive effect of OsDXR on carotenoid and chlorophyll metabolism in rice leaves. OsDXR-mediated transcriptional alteration of intrinsic carotenogenetic genes in rice leaves and seeds, overview 762871
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267physiological function enzyme SaDXR protein may be involved in plastidial isoprenoid biosynthesis in plants 763120
Show all pathways known for 1.1.1.267Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.267physiological function in many pathogenic bacteria, the enzymes of the 2-C-methyl-D-erythrirol 4-phosphate (MEP) pathway are involved in the biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate, the two universal and essential units for the biosynthesis of isoprenoids. The enzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR) that catalyzes the transformation of 1-deoxy-D-xylulose 5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) via an isomerization and a NADPH-dependent reduction reaction -, 762794
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