EC Number |
General Information |
Reference |
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1.1.1.267 | metabolism |
the enzyme is involved in a parasite-specific, isoprenoid biosynthetic DOXP/MEP pathway |
724558 |
1.1.1.267 | metabolism |
the enzyme is involved in the isoprenoid biosynthetic DOXP/MEP pathway |
724558 |
1.1.1.267 | physiological function |
in transgenic spike lavender plants (Lavandula latifolia) constitutively expressing the Arabidopsis thaliana DXR gene, a clear correlation between transcript accumulation and monoterpene production cannot be established. The DXR enzyme does not play a crucial role in the synthesis of plastidial monoterpene precursors |
736693 |
1.1.1.267 | metabolism |
induction of DXR expression causes increased thymol and carvacrol production |
748373 |
1.1.1.267 | metabolism |
the enzyme catalyzes the first comitted step in the methyl erythritol phosphate (MEP) pathway |
-, 760333 |
1.1.1.267 | metabolism |
the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) is the rate-limiting enzyme in the methylerythritol 4-phosphate pathway (MEP) via conversion of 1-deoxy-D-xylulose-5-phosphate (DXP) into MEP |
762525 |
1.1.1.267 | more |
enzyme CaDXR contains three conserved domain, namely NADPH (GSTGSIGT and LAAGSNV), substrate binding (LPADSEHSAI and NKGLEVIEAHY) and Cys-Ser-(Ala/Met/Val/Thr) cleavage-site domains. Three-dimensional molecular modeling and model validation, and molecular dynamics simulation of modeled DXR, overview |
762525 |
1.1.1.267 | physiological function |
the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), an NADPH-dependent reductase, plays a pivotal role in the methylerythritol 4-phosphate pathway (MEP), in the conversion of 1-deoxy-D-xylulose-5-phosphate (DXP) into MEP. Structure-function analysis of DXR and regulatory mechanism, molecular dynamics simulations, overview |
762525 |
1.1.1.267 | metabolism |
1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is the first key enzyme in the MEP pathway for terpenoid biosynthesis |
762667 |
1.1.1.267 | metabolism |
the enzyme is involved in the 2-methyl-D-erythritol-4-phosphate (MEP) terpenoid biosynthetic pathway catalyzing the second step, pathway overview |
-, 762747 |