EC Number   |
Expression |
Reference |
|---|
   2.7.11.31 | down |
alpha1 and alpha2 AMPK siRNAs selectively suppress AMPKalpha1 and AMPKalpha2 protein, respectively. AMPKalpha1 and AMPKalpha2 proteins are reduced to 6 and 1% of respective controls. Combined treatment with both alpha1 and alpha2 AMPK siRNAs lead to 66 and 92% reduction of AMPKalpha1 and AMPKalpha2 protein, respectively |
704459 |
| 2.7.11.31 | down |
loss of AMPK beta-subunit expression in beta1-/- and beta2-/- mice, leading to a low-bone-mass phenotype |
-, 703618 |
| 2.7.11.31 | down |
siRNA knockdown of AMPK, which ameliorates the IFNgamma-induced increase in epithelial permeability and decrease in transepithelial electrical resistance |
704545 |
| 2.7.11.31 | more |
overexpression of AMPK dominant negative mutant abolishes statin-induced reduction of O2- in BAEC |
704431 |
| 2.7.11.31 | up |
3 days of recurrent insulin-induced hypoglycaemia results in an increase in the gene expression of alpha1- and alpha2AMPK in the whole hypothalamus and in the dorso-mediobasal hypothalamus |
705267 |
| 2.7.11.31 | up |
AMPKalpha mRNA levels increase continuously throughout exposure to 26°C, reaching 5.6times more after 6 h at 26°C than in the 12°C controls |
704861 |
| 2.7.11.31 | up |
AMPKalpha1 repression causes a 37% compensational increase in AMPKalpha2 protein |
704459 |
| 2.7.11.31 | up |
enzyme activity significantly increases during ischemia, remaining activated during reperfusion |
762101 |
| 2.7.11.31 | up |
in the muscle subunit AMPK-gamma mRNA is significantly up-regulated at low salinity relative to controls. Muscle and hepatopancreas show increases in enzyme protein after 6 h exposure to low salinity, but there are no differences seen after long term acclimation |
760911 |
| 2.7.11.31 | up |
relative expression of alpha, beta, and gamma isoforms of AMPK is greatest in muscle and MAC-T cells |
702075 |
