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EC Number
Metals/Ions
Commentary
Reference
4.2.3.12
Zn2+
-
648553
,
702280
,
704296
4.2.3.12
Sr2+
5 mM greatly accelerates activity
648561
4.2.3.12
Ca2+
65% of the activity with equal concentration of Mg2+
648564
4.2.3.12
Ni2+
71% of the activity with Mg2+ with NiCl2, 5 mM
648554
4.2.3.12
Mg2+
75% enhancement
716147
4.2.3.12
Zn2+
bound to the enzyme
648554
4.2.3.12
Zn2+
bound to the Nepsilon-atoms of the three His residues HisA23, HisA48, and HisA50, one to each of the two active sites
648560
4.2.3.12
Zn2+
concentrations higher than 0.15 mM completely inactivates the enzyme
648554
4.2.3.12
more
Cu2+ has no effect on activity
648561
4.2.3.12
more
Cu2+, Fe2+, less than 15% of activity with Mg2+ with 5 mM of each ion
648554
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