EC Number   |
Metals/Ions |
Reference  |
|---|
    4.2.3.12 | Mg2+ |
required |
648553, 648555 |
| 4.2.3.12 | Ca2+ |
less than 15% of activity with Mg2+ with 5 mM |
648554 |
| 4.2.3.12 | Co2+ |
free metal enzyme activity reaches 60% of activity of wild type with 0.50 mM and concentrations higher than 0.15 mM completely inactivates the enzyme. Less than 15% of activity with Mg2+ with 5 mM |
648554 |
| 4.2.3.12 | Mg2+ |
free metal enzyme activity is 15% of the wild type with 8 mM, it is not bound to the enzyme |
648554 |
| 4.2.3.12 | Mn2+ |
less than 15% of activity with Mg2+ with 5 mM |
648554 |
| 4.2.3.12 | more |
Cu2+, Fe2+, less than 15% of activity with Mg2+ with 5 mM of each ion |
648554 |
| 4.2.3.12 | Ni2+ |
71% of the activity with Mg2+ with NiCl2, 5 mM |
648554 |
| 4.2.3.12 | Zn2+ |
bound to the enzyme |
648554 |
| 4.2.3.12 | Zn2+ |
concentrations higher than 0.15 mM completely inactivates the enzyme |
648554 |
| 4.2.3.12 | Zn2+ |
free metal enzyme activity reaches 85% of activity of wild type with 0.05 mM and 8 mM Mg2+ |
648554 |
