EC Number   |
Metals/Ions |
Reference |
|---|
  3.5.1.69 | Ba2+ |
10 mM, slight activation |
171986 |
| 3.5.1.69 | Ca2+ |
activation |
652249 |
| 3.5.1.69 | Ca2+ |
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme |
733197 |
| 3.5.1.69 | Ca2+ |
required, activtes. GM1 hydrolysis increases with increasing Ca 2+ concentration, compared with 40.7% yield in the absence of Ca2+, the addition of 100 mM Ca2+ enhances the yield to 81.6%. Best at 50-100 mM |
754363 |
| 3.5.1.69 | Co2+ |
activates, but slightly less effectve compared to Ca2+, at 100 mM |
754363 |
| 3.5.1.69 | Co2+ |
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme |
733197 |
| 3.5.1.69 | Fe2+ |
promotes the hydrolytic activity but inhibits the synthetic activity of the enzyme |
733197 |
| 3.5.1.69 | Mg2+ |
10 mM, slight activation |
171986 |
| 3.5.1.69 | Mg2+ |
activates, but less effectve compared to Ca2+, at 100 mM |
754363 |
| 3.5.1.69 | Mg2+ |
activation |
652249 |
