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EC Number
Metals/Ions
Commentary
Reference
2.4.1.149
Ca2+
about one third of the activity compared to Mn2+, recombinant enzyme
658728
2.4.1.149
Ca2+
activates, 48% as effective as Mn2+
638606
2.4.1.149
Cd2+
CdCl2 slightly stimulates
489473
2.4.1.149
Co2+
activates, 52% as effective as Mn2+
638606
2.4.1.149
Co2+
slightly stimulates, 12.8% as effective as Mn2+ at 10 mM
638578
2.4.1.149
Mg2+
about one third of the activity compared to Mn2+, recombinant enzyme
658728
2.4.1.149
Mg2+
MgCl2 slightly stimulates
489473
2.4.1.149
Mn2+
essential for activity, neither Mg2+ nor Ca2+ can substitute for Mn2+
638575
2.4.1.149
Mn2+
MnCl2 stimulates 2.5fold, optimal concentration: 20 mM
638577
2.4.1.149
Mn2+
MnCl2: 10-25 mM for optimal activity required
489473
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