EC Number   |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference  |
|---|
    1.14.16.2 | 0.058 |
- |
2-amino-4-hydroxy-6-methyl-5,6,7,8-tetrahydropteridine |
- |
438688, 438698 |
| 1.14.16.2 | -999 |
- |
more |
phosphorylation converts the enzyme from a form possessing a high Km for pterin cofactor to a form with a low Km for pterin cofactor |
438690 |
| 1.14.16.2 | 0.075 |
- |
tyrosine |
with 6-methyltetrahydropterin |
438690 |
| 1.14.16.2 | 0.006 |
- |
O2 |
below, recombinant enzyme |
438692 |
| 1.14.16.2 | 0.0094 |
- |
tyrosine |
recombinant enzyme, pH-independent |
438692 |
| 1.14.16.2 | 0.021 |
- |
Tetrahydropterin |
recombinant enzyme, value is pH-dependent |
438692 |
| 1.14.16.2 | -999 |
- |
more |
Km is dependent on substrate and cofactor concentration when (6R)-L-erythro-tetrahydrobiopterin is used due to inhibitory effects |
438694 |
| 1.14.16.2 | 0.011 |
- |
tyrosine |
- |
438703 |
| 1.14.16.2 | 0.06 |
0.1 |
6-Methyl-5,6,7,8-tetrahydropterin |
- |
438703 |
| 1.14.16.2 | 0.085 |
- |
phenylalanine |
- |
438703 |
